跨膜蛋白16A/钙激活氯离子通道抗体

适应物种 ：Human,Mouse,Rat,Dog,Pig,Cow,Horse,

应用范围 ：WB,

抗体英文名 ：ANO1/TMEM16A

规格 ：50ul

英文名称	ANO1/TMEM16A
中文名称	跨膜蛋白16A/钙激活氯离子通道抗体
别    名	ANO 1;ANO1_HUMAN; Anoctamin 1; Anoctamin 1 calcium activated chloride channel; Anoctamin-1; Anoctamin1; Discovered on gastrointestinal stromal tumors protein 1; DOG 1; FLJ10261; Membrane protein; Oral cancer overexpressed 2; Oral cancer overexpressed protein 2; ORAOV 2; ORAOV2; TAOS 2; TAOS2; TMEM 16A; TMEM16A; Transmembrane protein 16A (eight membrane spanning domains); Transmembrane protein 16A; Tumor amplified and overexpressed sequence 2; Tumor-amplified and overexpressed sequence 2.
研究领域	肿瘤  细胞生物  免疫学
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, )
产品应用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量	114kDa
细胞定位	细胞浆 细胞膜
性    状	Liquid
浓    度	1mg/ml
免 疫 原	KLH conjugated synthetic peptide derived from human DOG-1/TMEM16A:151-250/986
亚    型	IgG
纯化方法	affinity purified by Protein A
储 存 液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
产品介绍	TMEM16A (Transmembrane protein 16A) is an eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products and is amplified in various cancers. It acts as a calcium-activated chloride channel and is required for normal tracheal development. Function: Acts as a calcium-activated chloride channel. Required for normal tracheal development (By similarity). Subcellular Location: Cell membrane; Multi-pass membrane protein. Cytoplasm. Tissue Specificity: Broadly expressed with higher levels in liver and skeletal muscle. Similarity: Belongs to the anoctamin family. SWISS: Q5XXA6 Gene ID: 55107 Database links: Entrez Gene: 55107 Human Entrez Gene: 101772 Mouse Entrez Gene: 309135 Rat Omim: 610108 Human SwissProt: Q5XXA6 Human SwissProt: Q8BHY3 Mouse Unigene: 503074 Human Unigene: 26700 Mouse Unigene: 162509 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.