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适应物种 ：Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,
应用范围 ：ICC,
抗体英文名 ：SM22 Alpha
规格 ：50ul
| 英文名称 | SM22 Alpha |
| 中文名称 | 细胞骨架相关蛋白抗体 |
| 别 名 | 22 kDa actin binding protein; 22 kDa actin-binding protein; Transgelin; DKFZp686P11128; Human 22kDa smooth muscle protein; Protein WS3-10; SM22 alpha; SM22; SM22-alpha; SMCC; Smooth muscle protein 22-alpha; TAGL_HUMAN; TAGLN; TAGLN1; transgelin; Transgelin variant 2; WS3 10; Protein WS3-10; WS3-10. |
| 研究领域 | 心血管 细胞生物 信号转导 细胞骨架 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, ) |
| 产品应用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test ICC= IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 22kDa |
| 细胞定位 | 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SM22 Alpha:101-201/201 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] Function: Actin cross-linking/gelling protein. Involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence. Subcellular Location: Cytoplasm (Probable). Similarity: Belongs to the calponin family. Contains 1 calponin-like repeat. Contains 1 CH (calponin-homology) domain. SWISS: Q01995 Gene ID: 6876 Database links: Entrez Gene: 6876 Human Entrez Gene: 8407 Human Entrez Gene: 21345 Mouse Omim: 600818 Human SwissProt: Q01995 Human SwissProt: P37804 Mouse Unigene: 410977 Human Unigene: 666842 Human Unigene: 283283 Mouse Unigene: 34397 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. SM22α蛋白是一种细胞骨架相关蛋白. |
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