骨形态发生蛋白2抗体

适应物种 ：Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Guinea Pig,

应用范围 ：WB,

抗体英文名 ：BMP2

规格 ：50ul

英文名称	BMP2
中文名称	骨形态发生蛋白2抗体
别    名	Bone morphogenetic protein 2; BMP 2; BMP 2A; BMP2A; BMP-2; BMP2_HUMAN.
研究领域	细胞生物  免疫学  发育生物学  神经生物学  生长因子和激素
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Cow, Horse, Guinea Pig, )
产品应用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量	13/44kDa
细胞定位	分泌型蛋白
性    状	Liquid
浓    度	1mg/ml
免 疫 原	KLH conjugated synthetic peptide derived from human BMP2:341-396/396
亚    型	IgG
纯化方法	affinity purified by Protein A
储 存 液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
产品介绍	BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. BMPs control fundamental events in early embryonic development, organogenesis and adult tissue homeostasis. Function: Induces cartilage and bone formation. Subunit: Homodimer; disulfide-linked. Interacts with SOSTDC1. Interacts with GREM2, RGMA, RGMB and RGMC. Interacts with ASPN. Subcellular Location: Secreted. Tissue Specificity: Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine. Similarity: Belongs to the TGF-beta family. SWISS: P12643 Gene ID: 650 Database links: Entrez Gene: 650 Human Entrez Gene: 12156 Mouse Entrez Gene: 29373 Rat Omim: 112261 Human SwissProt: P12643 Human SwissProt: P21274 Mouse SwissProt: P49001 Rat Unigene: 73853 Human Unigene: 103205 Mouse Unigene: 90931 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.