类肿瘤性抗原MA3抗体

适应物种 ：Mouse,Rat,

应用范围 ：WB,

抗体英文名 ：PNMA3

规格 ：100ul

英文名称	PNMA3
中文名称	类肿瘤性抗原MA3抗体
别    名	MA3; MA5; MGC132756; MGC132758; Paraneoplastic antigen Ma3; Paraneoplastic cancer testis brain antigen; Paraneoplastic Ma antigen 3; PNMA 3; PNMA3; PNMA3_MOUSE.
研究领域	肿瘤  细胞生物
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Mouse,  (predicted: Rat, )
产品应用	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量	52kDa
细胞定位	细胞核
性    状	Liquid
浓    度	1mg/ml
免 疫 原	KLH conjugated synthetic peptide derived from mouse PNMA3:351-450/463
亚    型	IgG
纯化方法	affinity purified by Protein A
储 存 液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
产品介绍	The protein encoded by this gene belongs to the paraneoplastic antigen MA (PNMA) family, which shares homology with retroviral Gag proteins. The PNMA antigens are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] Subcellular Location: Nucleus > nucleolus. Tissue Specificity: Expressed at high levels in the brain and testis. Expressed at lower levels in the heart, trachea and kidney. Similarity: Belongs to the PNMA family. Contains 1 CCHC-type zinc finger. SWISS: Q8JZW8 Gene ID: 245468 Database links: Entrez Gene: 29944 Human Entrez Gene: 245468 Mouse GenBank: NP_037496 Human Omim: 300675 Human SwissProt: Q9UL41 Human SwissProt: Q8JZW8 Mouse Unigene: 449627 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications