产品详情
文献和实验
相关推荐
靶点 :EDN3
浓度 :1 mg/mL.
应用范围 :WB,IF-Cell,IHC-P
宿主 :Rabbit
适应物种 :Human,Mouse,Rat
保质期 :1年
供应商 :Huabio
标记物 :Non-conjugated
保存条件 :Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
形态 :Liquid
亚型 :IgG
免疫原 :Synthetic peptide within human Endothelin 3 aa 80-130.
规格 :50μl/100μl
The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms.杭州华安生物技术有限公司
品牌商实名认证
钻石会员
入驻年限:7年