Artn Polyclonal Antibody/Artn Polyclonal Antibody

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英文名 ：Artn Polyclonal Antibody

库存 ：现货

供应商 ：亚科因

CAS号 ：Null

规格 ：30μl///100μl///200μl

关键词：Artn抗体;神经鞘胚素蛋白artemin抗体;神经鞘胚素蛋白artemin;Artemin; Enovin; Neublastin;ABP57821

中文名称：神经鞘胚素蛋白artemin多克隆抗体/Artn Polyclonal Antibody

英文名称：Artn Polyclonal Antibody

产品说明书：http://www.abbkine.cn/datasheet/ABP57821.pdf

产品描述：兔抗-神经鞘胚素蛋白artemin 多克隆抗体

ARTN encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma.

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