转化生长因子β2多克隆抗体/TGFβ2 Polyclonal Antibody

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英文名 ：TGFβ2 Polyclonal Antibody

库存 ：现货

供应商 ：亚科因

CAS号 ：Null

规格 ：30μl///100μl///200μl

关键词：TGFβ2抗体;转化生长因子β2抗体;转化生长因子β2;Transforming growth factor beta-2; TGF-beta-2; BSC-1 cell growth inhibitor; Cetermin; Glioblastoma-derived T-cell suppressor factor; G-TSF; Polyergin;ABP60666

中文名称：转化生长因子β2多克隆抗体/TGFβ2 Polyclonal Antibody

英文名称：TGFβ2 Polyclonal Antibody

产品说明书：http://www.abbkine.cn/datasheet/ABP60666.pdf

产品描述：兔抗-转化生长因子β2多克隆抗体

TGFβ2 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Disruption of the TGF-beta/SMAD pathway has been implicated in a variety of human cancers. A chromosomal translocation that includes this gene is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. Mutations in this gene may be associated with Loeys-Dietz syndrome. TGFβ2 encodes multiple isoforms that may undergo similar proteolytic processing.

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