固醇调节因子结合蛋白1多克隆抗体/SREBP-1 Polyclonal Antibody

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英文名 ：SREBP-1 Polyclonal Antibody

库存 ：现货

供应商 ：亚科因

CAS号 ：Null

规格 ：30μl///100μl///200μl

关键词：SREBP-1抗体;固醇调节因子结合蛋白1抗体;固醇调节因子结合蛋白1;Sterol regulatory element-binding protein 1; SREBP-1; Class D basic helix-loop-helix protein 1; bHLHd1; Sterol regulatory element-binding transcription factor 1;ABP60509

中文名称：固醇调节因子结合蛋白1多克隆抗体/SREBP-1 Polyclonal Antibody

英文名称：SREBP-1 Polyclonal Antibody

产品说明书：http://www.abbkine.cn/datasheet/ABP60509.pdf

产品描述：兔抗-固醇调节因子结合蛋白1 多克隆抗体

SREBF1 encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1， which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. SREBF1 is located within the Smith-Magenis syndrome region on chromosome 17.

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