鸟嘌呤核苷酸结合蛋白G, β3多克隆抗体/GBB3 Polyclonal Antibody

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英文名 ：GBB3 Polyclonal Antibody

库存 ：现货

供应商 ：亚科因

CAS号 ：Null

规格 ：30μl///100μl///200μl

关键词：GBB3抗体;鸟嘌呤核苷酸结合蛋白G, β3抗体;鸟嘌呤核苷酸结合蛋白G, β3;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Transducin beta chain 3;ABP58611

中文名称：鸟嘌呤核苷酸结合蛋白G, β3多克隆抗体/GBB3 Polyclonal Antibody

英文名称：GBB3 Polyclonal Antibody

产品说明书：http://www.abbkine.cn/datasheet/ABP58611.pdf

产品描述：兔抗-鸟嘌呤核苷酸结合蛋白G, β3 多克隆抗体

Heterotrimeric guanine nucleotide-binding proteins (G proteins， which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. GNB3 encodes a beta subunit which belongs to the WD repeat G protein beta family. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

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