视网膜G蛋白偶联受体多克隆抗体/RGR Polyclonal Antibody

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英文名 ：RGR Polyclonal Antibody

库存 ：现货

供应商 ：亚科因

CAS号 ：Null

规格 ：30μl///100μl///200μl

关键词：RGR抗体;视网膜G蛋白偶联受体抗体;视网膜G蛋白偶联受体;RGR; RPE-retinal G protein-coupled receptor;ABP56042

中文名称：视网膜G蛋白偶联受体多克隆抗体/RGR Polyclonal Antibody

英文名称：RGR Polyclonal Antibody

产品说明书：http://www.abbkine.cn/datasheet/ABP56042.pdf

产品描述：兔抗-视网膜G蛋白偶联受体 多克隆抗体

RGR (retinal G protein coupled receptor) encodes a putative retinal G-protein coupled receptor. RGR is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. RGR may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.

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