细胞周期素依赖性激酶4多克隆抗体/Cdk4 Polyclonal Antibody

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英文名 ：Cdk4 Polyclonal Antibody

库存 ：现货

供应商 ：亚科因

CAS号 ：Null

规格 ：30μl///100μl///200μl

关键词：Cdk4抗体;细胞周期素依赖性激酶4抗体;细胞周期素依赖性激酶4;CDK4; Cyclin-dependent kinase 4; Cell division protein kinase 4; PSK-J3;ABP52929

中文名称：细胞周期素依赖性激酶4多克隆抗体/Cdk4 Polyclonal Antibody

英文名称：Cdk4 Polyclonal Antibody

产品说明书：http://www.abbkine.cn/datasheet/ABP52929.pdf

产品描述：兔抗-细胞周期素依赖性激酶4 多克隆抗体

Cyclin-dependent kinase 4 encoded by CDK4 is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16 (INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16 (INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.

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