端粒酶相反转录酶多克隆抗体/TERT Polyclonal Antibody

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英文名 ：TERT Polyclonal Antibody

库存 ：现货

供应商 ：亚科因

CAS号 ：Null

规格 ：30μl///100μl///200μl

关键词：TERT抗体;端粒酶相反转录酶抗体;端粒酶相反转录酶;TERT; EST2; TCS1; TRT; Telomerase reverse transcriptase; HEST2; Telomerase catalytic subunit; Telomerase-associated protein 2; TP2;ABP52582

中文名称：端粒酶相反转录酶多克隆抗体/TERT Polyclonal Antibody

英文名称：TERT Polyclonal Antibody

产品说明书：http://www.abbkine.cn/datasheet/ABP52582.pdf

产品描述：兔抗-端粒酶相反转录酶 多克隆抗体

Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity.

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