CD47 : SIRP alpha[生物素标记]抑制剂筛选试剂盒(ELISA)

保存条件 ：Upon receipt, please store all items at -70°C. After reconstitution, the stock solution should be kept at -70°C.

英文名 ：CD47 : SIRP alpha [Biotinylated] Inhibitor Screening ELISA Assay Pair

库存 ：1

供应商 ：ACROBiosystems

规格 ：96tests

Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.