KIT (V560D)

免疫原 ：A synthetic peptide from the internal region of KIT which includes the mutation of V560D, human origin.

亚型 ：lgG

形态 ：液体

保存条件 ：-20℃

克隆性 ：单克隆

标记物 ：FITC

适应物种 ：脊椎动物

保质期 ：24个月

抗原来源 ：蛋白

目录编号 ：TD-26281

级别 ：科研级

库存 ：999

供应商 ：武汉天德

宿主 ：Mouse

应用范围 ：ELISA, WB

浓度 ：1mg/ml

靶点 ：V560D

抗体英文名 ：Anti-KIT (V560D) mouse monoclonal antibody

抗体名 ：KIT(V560D) 

规格 ：100 μL

KIT(V560D) 

Cat. #:  TD-26281

Gene Symbol:  C-Kit; CD117; KIT; PBT; SCFR

Description:   Anti-KIT(V560D) Mouse Monoclonal Antibody

Background:   Tyrosine-protein kinase Kit, also known as proto-oncogene c-Kit or CD117 or Mast/stem cell growth factor receptor (SCFR), is a receptor tyrosine kinase protein that in humans is encoded by the KIT gene. Activating mutations in this gene are associated with gastrointestinal stromal tumors, testicular seminoma, mast cell disease, melanoma, acute myeloid leukemia, while inactivating mutations are associated with the genetic defect piebaldism.

Immunogen:   A synthetic peptide from the internal region of KIT which includes the mutation of V560D, human origin.

Applications:   ELISA, WB

Recommended Dilutions:    ELISA: 1:1000-1:5000 WB: 1:500-1:1000

Concentration:   1 mg/ml

Host Species:   Mouse

Format:   Liquid

Clonality:   Monoclonal

Isotype:   IgG

Purity:   Purified from ascites

Preservative: No

Constituents:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity:  Recognizes V560D mutant, but not wild type KIT of vertebrates.

Storage Conditions:   Store at -20°C. Avoid repeated freezing and thawing

Western blot:    Western blot analysis of recombinant KIT(V560D) and wild type proteins. Purified His-tagged KIT(V560D) protein (lane 2) and corresponding wild type protein (lane 1) were blotted with Anti-KIT(V560D) monoclonal antibody (Cat. #TD-26281).