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免疫原 :A synthetic peptide from the internal region of SMO which includes the mutation of A68V, human origin.
亚型 :lgG
形态 :液体
保存条件 :-20℃
克隆性 :单克隆
标记物 :FITC
适应物种 :脊椎动物
保质期 :24个月
抗原来源 :蛋白
目录编号 :TD-26425
级别 :科研级
库存 :999
供应商 :武汉天德
宿主 :Mouse
应用范围 :ELISA, WB, IHC
浓度 :1mg/ml
靶点 :A68V
抗体英文名 :Anti-SMO (A68V) mouse monoclonal antibody
抗体名 :SMO(A68V)
规格 :100 μL
SMO(A68V)
Cat. #: TD-26425 |
Size: 100 µL |
Gene Symbol: SMO; MRD21 |
Description: Anti-SMO(A68V) Mouse Monoclonal Antibody |
Background: Smoothened is a protein that in humans is encoded by the SMO gene. Smoothened is a G protein-coupled receptor that is a component of the hedgehog signaling pathway and is conserved from flies to humans. It is the molecular target of the teratogen cyclopamine. SMO can function as an oncogene. Activating SMO mutations can lead to unregulated activation of the hedgehog pathway and cancer |
Immunogen: A synthetic peptide from the internal region of SMO which includes the mutation of A68V, human origin. |
Applications: ELISA, WB, IHC |
Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:500-1:1000 IHC: 1:50-1:100 |
Concentration: 1 mg/ml |
Host Species: Mouse |
Format: Liquid |
Clonality: Monoclonal |
Isotype: IgG |
Purity: Purified from ascites |
Preservative: No |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Recognizes A68V mutant, but not wild type SMO of vertebrates. |
Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Western blot:
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Immunofluorescence:
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入驻年限:5年