阿狄科®大/小鼠S100A8/A9蛋白检测试剂盒（酶联免疫法）价格

库存：10

供应商：广东固康生物科技有限公司

检测限：——

检测方法：酶联免疫法

应用：——

适应物种：大/小鼠

标记物：——

样本：血清/血浆

规格：96人份/盒

【产品名称】
通用名称：阿狄科®大/小鼠S100A8/A9蛋白检测试剂盒（酶联免疫法）
英文名称：IDK® S100A8/A9 (MRP8/14, Calprotectin, Mouse/Rat)

【预期用途】
用于定量测定粪便、血清、血浆、尿液、组织提取物和细胞培养上清液中的 S100A8/S100A9（钙卫蛋白，MRP 8/14）。仅供科研使用，不用于诊断目的。

【背景知识】
替代名称：
钙粒蛋白 A：MRP8、S100A8、CP-10。
钙粒蛋白 B：MRP14、S100A9
钙卫蛋白, MRP8/14:L1,(p8,14), p34
S100A8/S100A9 (MRP 8/14) 是一种由中性粒细胞和单核细胞产生的钙结合蛋白。面部 S100A8/S100A9 是炎症和肿瘤起源的胃肠道疾病的标志物。
通常很难区分 IBS 患者和慢性炎症性肠病 (IBD) 患者。这导致了许多不必要的结肠镜检查。这两个患者组现在可以使用 S100A8/S100A9 测试清楚地区分彼此。以及以前评估 IBD 活动的金标准，测量粪便中铟-111-的排泄量标记中性粒细胞的患者，因此不建议儿童和孕妇重复使用。

参考文献：
1. Hildebrand, F. et al, 2013. Inflammation-associated enterotypes, host genotype,cage and inter-individual effects drive gut microbiota variation in common labo-ratory mice.Genome biology,14(1), p.R4.
2.Nelson,D.a et al., 2012.An expanded myeloid derived suppressor cell populationdoes not play a role in gammaherpesvirus-exacerbated breast cancer metastases.lnfectious agents and cancer, 7(1), p.22.
3. Prinzen,C. et al，2009.Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice.BMC genomics,10, p.66.
4. Soro-Paavonen,A. et al., 2008.Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes. Di-abetes, 57(9), pp.2461-2469.
5. Volz, H.C.et al., 2012.S100A8/A9 aggravates post-ischemic heart failure through activation of RAGE-dependent NF-xB signaling. Basic research in cardiology,107(2),p.250.
6. Wiechert, L. et al, 2012.Hepatocyte-specific S100a8 and S100a9 transgene ex-pression in mice causes Cxcl1 induction and systemic neutrophil enrichment. Cellcommunication and signaling : CCS, 10(1), p.40.
7. Yamamoto, Y.et al., 2011. Septic shock is associated with receptor for advanced glycation end products ligation of LPS. Journal of immunology (Baltimore,Md.:1950),186(5), pp.3248-57.

该产品被引用文献

1. Hildebrand, F. et al, 2013. Inflammation-associated enterotypes, host genotype,cage and inter-individual effects drive gut microbiota variation in common labo-ratory mice.Genome biology,14(1), p.R4.
2.Nelson,D.a et al., 2012.An expanded myeloid derived suppressor cell populationdoes not play a role in gammaherpesvirus-exacerbated breast cancer metastases.lnfectious agents and cancer, 7(1), p.22.
3. Prinzen,C. et al，2009.Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice.BMC genomics,10, p.66.
4. Soro-Paavonen,A. et al., 2008.Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes. Di-abetes, 57(9), pp.2461-2469.
5. Volz, H.C.et al., 2012.S100A8/A9 aggravates post-ischemic heart failure through activation of RAGE-dependent NF-xB signaling. Basic research in cardiology,107(2),p.250.
6. Wiechert, L. et al, 2012.Hepatocyte-specific S100a8 and S100a9 transgene ex-pression in mice causes Cxcl1 induction and systemic neutrophil enrichment. Cellcommunication and signaling : CCS, 10(1), p.40.
7. Yamamoto, Y.et al., 2011. Septic shock is associated with receptor for advanced glycation end products ligation of LPS. Journal of immunology (Baltimore,Md.:1950),186(5), pp.3248-57.