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Biacore传感器芯片用于通过金属螯合捕获和固定组氨酸标记分子。
基质：氮川三乙酸(NTA*)预固化的羧甲基化右旋糖酐。 多聚组氨酸标记分子通过Ni?2+/NTA螯合作用进行固化。 标记分子相互作用相关信息，比如重组蛋白，对被标记蛋白相关其他技术所获取的信息进行补充。
请注意，Biacore传感器芯片有两种格式。该产品适合 Biacore 8K、Biacore S200、Biacore T200/T100、Biacore4000/A100、Biacore S51
产品被引用文献：
[1] Segala E, Errey JC, Fiez-Vandal C, Zhukov A, Cooke RM. Biosensor-based affinities and binding kinetics of small molecule antagonists to the adenosine A(2A) receptor reconstituted in HDL like particles. FEBS Lett. 2015 Jun 4;589(13):1399-405. doi: 10.1016/j.febslet.2015.04.030. Epub 2015 Apr 29. PMID: 25935416.
[2] Cheng RKY, Fiez-Vandal C, Schlenker O, Edman K, Aggeler B, Brown DG, Brown GA, Cooke RM, Dumelin CE, Doré AS, Geschwindner S, Grebner C, Hermansson NO, Jazayeri A, Johansson P, Leong L, Prihandoko R, Rappas M, Soutter H, Snijder A, Sundström L, Tehan B, Thornton P, Troast D, Wiggin G, Zhukov A, Marshall FH, Dekker N. Structural insight into allosteric modulation of protease-activated receptor 2. Nature. 2017 May 4;545(7652):112-115. doi: 10.1038/nature22309. Epub 2017 Apr 26. PMID: 28445455.
[3] Turnbull AP, Ioannidis S, Krajewski WW, Pinto-Fernandez A, Heride C, Martin ACL, Tonkin LM, Townsend EC, Buker SM, Lancia DR, Caravella JA, Toms AV, Charlton TM, Lahdenranta J, Wilker E, Follows BC, Evans NJ, Stead L, Alli C, Zarayskiy VV, Talbot AC, Buckmelter AJ, Wang M, McKinnon CL, Saab F, McGouran JF, Century H, Gersch M, Pittman MS, Marshall CG, Raynham TM, Simcox M, Stewart LMD, McLoughlin SB, Escobedo JA, Bair KW, Dinsmore CJ, Hammonds TR, Kim S, Urbé S, Clague MJ, Kessler BM, Komander D. Molecular basis of USP7 inhibition by selective small-molecule inhibitors. Nature. 2017 Oct 26;550(7677):481-486. doi: 10.1038/nature24451. Epub 2017 Oct 18. PMID: 29045389; PMCID: PMC6029662.
基质：氮川三乙酸(NTA*)预固化的羧甲基化右旋糖酐。 多聚组氨酸标记分子通过Ni?2+/NTA螯合作用进行固化。 标记分子相互作用相关信息，比如重组蛋白，对被标记蛋白相关其他技术所获取的信息进行补充。
请注意，Biacore传感器芯片有两种格式。该产品适合 Biacore 8K、Biacore S200、Biacore T200/T100、Biacore4000/A100、Biacore S51
| 订货信息 | 货号 | 规格 |
| 28994951 | 一片装 | |
| BR100532 | 三片装 |
产品被引用文献：
[1] Segala E, Errey JC, Fiez-Vandal C, Zhukov A, Cooke RM. Biosensor-based affinities and binding kinetics of small molecule antagonists to the adenosine A(2A) receptor reconstituted in HDL like particles. FEBS Lett. 2015 Jun 4;589(13):1399-405. doi: 10.1016/j.febslet.2015.04.030. Epub 2015 Apr 29. PMID: 25935416.
[2] Cheng RKY, Fiez-Vandal C, Schlenker O, Edman K, Aggeler B, Brown DG, Brown GA, Cooke RM, Dumelin CE, Doré AS, Geschwindner S, Grebner C, Hermansson NO, Jazayeri A, Johansson P, Leong L, Prihandoko R, Rappas M, Soutter H, Snijder A, Sundström L, Tehan B, Thornton P, Troast D, Wiggin G, Zhukov A, Marshall FH, Dekker N. Structural insight into allosteric modulation of protease-activated receptor 2. Nature. 2017 May 4;545(7652):112-115. doi: 10.1038/nature22309. Epub 2017 Apr 26. PMID: 28445455.
[3] Turnbull AP, Ioannidis S, Krajewski WW, Pinto-Fernandez A, Heride C, Martin ACL, Tonkin LM, Townsend EC, Buker SM, Lancia DR, Caravella JA, Toms AV, Charlton TM, Lahdenranta J, Wilker E, Follows BC, Evans NJ, Stead L, Alli C, Zarayskiy VV, Talbot AC, Buckmelter AJ, Wang M, McKinnon CL, Saab F, McGouran JF, Century H, Gersch M, Pittman MS, Marshall CG, Raynham TM, Simcox M, Stewart LMD, McLoughlin SB, Escobedo JA, Bair KW, Dinsmore CJ, Hammonds TR, Kim S, Urbé S, Clague MJ, Kessler BM, Komander D. Molecular basis of USP7 inhibition by selective small-molecule inhibitors. Nature. 2017 Oct 26;550(7677):481-486. doi: 10.1038/nature24451. Epub 2017 Oct 18. PMID: 29045389; PMCID: PMC6029662.
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