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应用范围 :Immunofluorescence;Immunoprecipitation
宿主 :Mouse
库存 :大量
适应物种 :Human;Mouse
抗原来源 :0
是否单克隆 :1
规格 :100 μg
Species Reactivity | Key Applications | Host | Format | Antibody Type |
---|---|---|---|---|
H, M | IF, IP, WB, IH | Mouse | Purified | Monoclonal Antibody |
Description:
Anti-APC, C-terminus, clone C-APC 28.9
Background Information:
The adenomatous polyposis coli tumor suppressor gene is mutated (often deletion of the C-terminal portion of APC) in the inherited disease, familial adenomatous polyposis (FAP), and over 80% of colorectal cancers. C-APC 28.8 can be used for APC expression and detection of APC mutations.
Alternate Names:
Adenomatous Polyposis Coli Protein
Clone:
C-APC 28.9
Specificity:
Recognizes human APC, molecular weight is approximately 310kDa.
Key Applications:
- Immunofluorescence
- Immunoprecipitation
- Western Blotting
- Immunohistochemistry
Application Notes:
Western blot
Immunohistochemistry (Frozen sections)
Immunofluorescence
Immunoprecipitation
Optimal working dilutions must be determined by end user.
Immunohistochemistry (Frozen sections)
Immunofluorescence
Immunoprecipitation
Optimal working dilutions must be determined by end user.
Species Reactivity:
- Human
- Mouse
Isotype:
IgG1κ
Immunogen:
Human APC C-terminal fusion with MBP (maltose binding protein).
Epitope:
C-terminus
Control:
POSITIVE CONTROL: colon cell line HCT116
Presentation:
Purified immunoglobulin. Liquid in 0.02M phosphate buffer, 0.25M NaCl, pH 7.6, with 0.1% sodium azide.
Storage Conditions:
Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt.
Gene Symbol:
- APC
- DP2.5
- FAP
- GS
- DP3
- DP2
- FPC
Antibody Category:
Epigenetics & Nuclear Function
Antibody Sub-Category:
Cell Cycle, DNA Replication & Repair
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Trade Name:
Chemicon (Millipore)
Format:
Purified
Host:
Mouse
Antibody Type:
Monoclonal Antibody
更多产品技术资讯,请访问密理博中国博客:http://blog.milliporechina.com
Human APC C-terminal fusion with MBP (maltose binding protein). 详细描述见链接:http://www.millipore.com/catalogue/item/MAB3786
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入驻年限:2年