Anti-APC, C-terminus, clone C-APC 28.9; 100 μg

Anti-APC, C-terminus, clone C-APC 28.9; 100 μg

价格: 询价

货号:MAB3786

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应用范围 :Immunofluorescence;Immunoprecipitation

宿主 :Mouse

库存 :大量

适应物种 :Human;Mouse

抗原来源 :0

是否单克隆 :1

规格 :100 μg

Species Reactivity Key Applications Host Format Antibody Type
H, M IF, IP, WB, IH Mouse Purified Monoclonal Antibody
Description:
Anti-APC, C-terminus, clone C-APC 28.9
Background Information:
The adenomatous polyposis coli tumor suppressor gene is mutated (often deletion of the C-terminal portion of APC) in the inherited disease, familial adenomatous polyposis (FAP), and over 80% of colorectal cancers. C-APC 28.8 can be used for APC expression and detection of APC mutations.
Alternate Names:
Adenomatous Polyposis Coli Protein
Clone:
C-APC 28.9
Specificity:
Recognizes human APC, molecular weight is approximately 310kDa.
Key Applications:
  • Immunofluorescence
  • Immunoprecipitation
  • Western Blotting
  • Immunohistochemistry
Application Notes:
Western blot

Immunohistochemistry (Frozen sections)

Immunofluorescence

Immunoprecipitation

Optimal working dilutions must be determined by end user.
Species Reactivity:
  • Human
  • Mouse
Isotype:
IgG1κ
Immunogen:
Human APC C-terminal fusion with MBP (maltose binding protein).
Epitope:
C-terminus
Control:
POSITIVE CONTROL: colon cell line HCT116
Presentation:
Purified immunoglobulin. Liquid in 0.02M phosphate buffer, 0.25M NaCl, pH 7.6, with 0.1% sodium azide.
Storage Conditions:
Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt.
Gene Symbol:
  • APC
  • DP2.5
  • FAP
  • GS
  • DP3
  • DP2
  • FPC
Antibody Category:
Epigenetics & Nuclear Function
Antibody Sub-Category:
Cell Cycle, DNA Replication & Repair
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Trade Name:
Chemicon (Millipore)
Format:
Purified
Host:
Mouse
Antibody Type:
Monoclonal Antibody

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Human APC C-terminal fusion with MBP (maltose binding protein). 详细描述见链接:http://www.millipore.com/catalogue/item/MAB3786

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