产品详情
文献和实验
相关推荐
靶点 :GATA3
浓度 :2 mg/ml.
应用范围 :WB,ICC,FC
宿主 :Mouse
适应物种 :Human
保质期 :1年
供应商 :Huabio
标记物 :Non-conjugated
保存条件 :Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
形态 :Liquid
亚型 :IgG2c
免疫原 :Synthetic peptide within N-terminal Human GATA3.
规格 :50μl/100μl
GATA3 is a transcription factor that in humans is encoded by the GATA3 gene. Studies in animal models and humans indicate that it controls the expression of a wide range of biologically and clinically important genes. The GATA3 transcription factor is critical for the embryonic development of various tissues as well as for inflammatory and humoral immune responses and the proper functioning of the endothelium of blood vessels. GATA3 haploinsufficiency (i.e. lose of one or the two inherited GATA3 genes) results in a congenital disorder termed the Barakat syndrome. Current clinical and laboratory research is focusing on determining the benefits of directly or indirectly blocking the action of GATA3 in inflammatory and allergic diseases such as asthma. It is also proposed to be a clinically important marker for various types of cancer, particularly those of the breast. However, the role, if any, of GATA3 in the development of these cancers is under study and remains unclear.杭州华安生物技术有限公司
品牌商实名认证
钻石会员
入驻年限:7年