Anti-Phospho ATF2 (T71) Antibody

价格： ￥1060 - 2580

品牌：BOSTER 品牌认证

货号：BM4466

产品详情

产品概况

货号	BM4466
产品名称	Anti-Phospho ATF2 (T71) Antibody
基因名	ATF2
抗体来源	Rabbit
克隆	Monoclonal
抗体亚型	Rabbit
分子量	65-75KD
免疫原	A synthesized peptide derived from human Phospho-ATF2 (T71)
内容	500 ug/ml;Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
纯化方式	Affinity-chromatography
浓度	500 ug/ml
产品形态	Liquid
保存条件	12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
背景资料	ATF2, also known as Activating transcription factor 2, is a protein that in humans is encoded by the ATF2 gene. It is mapped to 2q31.1. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA-binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus, it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.
研究类别	1. "Entrez Gene: ATF2 activating transcription factor 2"2. Bhoumik A, Takahashi S, Breitweiser W, Shiloh Y, Jones N, Ronai Z (May 2005). "ATM-dependent phosphorylation of ATF2 is required for the DNA damage response". Mol. Cell 18 (5): 577–87.
Uniprot ID	ATF2: P15336

产品应用细节

博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测，以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。

应用	稀释度*
Western blot(WB):	1:500-2000
Immunocytochemistry/Immunofluorescence(ICC/IF):	1:20-100
Immunocoprecipitation:	1:20

*最佳稀释度需要用户自己调试，此处数据仅供参考。

**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。

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[list_product_images]Western blot analysis of Phospho-ATF2 (T71) expression in (1) HeLa cell lysate; (2) HeLa cell lysate treated with Anisomycin.[/list_product_images]