PeproTech重组人IL-36γ 1000ug

价格：询价

品牌：PEPROTECH 品牌认证

货号：200-36G

产品详情

Recombinant Human IL-36γ (IL-1F9)

产品编号:

200-36G

别名:

IL-1F, IL-1ε (epsilon), IL-1H1

描述:

The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36 α (IL-1F6), β (IL-1F8) and γ (IL-1F9). IL-36γ is highly expressed in psoriatic plaques and in tissues containing epithelial cells. IL-36γ signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36γ also functions as an agonist of NF-kappaB, and can stimulate the inflammatory response in bronchial epithelial cells. Recombinant human IL-36γ is a 17.0 kDa protein containing 152 amino acid residues.

氨基酸序列:

SMCKPITGTI NDLNQQVWTL QGQNLVAVPR SDSVTPVTVA VITCKYPEAL EQGRGDPIYL GIQNPEMCLY CEKVGEQPTL QLKEQKIMDL YGQPEPVKPF LFYRAKTGRT STLESVAFPD WFIASSKRDQ PIILTSELGK SYNTAFELNI ND

来源:

E.coli

纯度:

Greater than 95% by SDS-PAGE gel and HPLC analyses.

生物活性:

Measured by its ability to induce IL-8 production by human PBMCs.

原产国:

USA

仅用于研究。不适用于诊断或治疗。