Mouse Anti-Human CD79 (B29 Ig), Antibody

保存条件 ：The purified (UNLB) antibody is supplied as 0.1 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0. No preservatives or amine-containing buffer salts added. Store at 2-8C.<br>The fluorescein (FITC) conjugate is supplied as 10

克隆性 ：单克隆

适应物种 ：Human

库存 ：大量

供应商 ：genway

应用范围 ：Flow Cytometry (FACS), IHC-F, IP

抗体英文名 ：Mouse Anti-Human CD79 (B29 Ig), Antibody

规格 ：100 TESTS

Similarity: Contains 1 ITAM domain. Schlossman, S., L. Bloumsell, W. Gilks, J.M. Harlan, C. Kishimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T.F. Tedder, and R.F. Todd, eds. 1995. Leukocyte Typing V White Cell Differentiation Antigens, Oxford University Press, Oxford.

Function: Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B cells.