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ACT-678689

CAS No. : 1783256-96-1

MCE 国际站：ACT-678689

产品活性：ACT-678689 (Compound Example 1.53.4) 是一种色氨酸羟化酶 (TPH) 抑制剂，IC₅₀ 为 8 nM。

研究领域：Metabolic Enzyme/Protease

作用靶点：Tryptophan Hydroxylase

In Vitro: TPH comprises two isoforms: TPH2 is mainly expressed in neuronal cell types in the central nervous system (CNS), while TPH1 is mainly expressed in peripheral tissues, including the entrochromaffin cells (EC) in the gut, where it is responsible for synthesizing 5HT that is stored in circulating blood platelets.

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