文献支持N-十二烷酰硫|N-Dodecanoyl-sulfatide

保存条件 ：建议在-20℃温度下冷冻保存

保质期 ：参考产品说明书

英文名 ：N-Dodecanoyl-sulfatide

库存 ：100

供应商 ：艾美捷科技

CAS号 ：无

规格 ：1mg

N-十二烷酰硫，N-Dodecanoyl-sulfatide，N-Dodecanoyl-sulfatide

产品名称：N-十二烷酰硫-N-Dodecanoyl-sulfatide

产品货号：1938-1

产品规格：1mg

背景资料：This product is a well-defined sulfatide containing a dodecanoic acid acylated to the amine of the sphingosine and is ideal as an internal standard. Sulfatide is a type of sulfolipid that is found primarily in the central nervous system and is a myelinspecific sphingolipid. A deficiency of sulfatide in white and gray matter has been associated with Alzheimer’s disease and other types of dementia. Apoliprotein E plays an important regulating role in the metabolism of sulfatides.1 The production of anti-sulfatide antibodies in the cerebrospinal fluid, leading to a deficiency in sulfatides, may be a cause of degeneration of the myelin sheath, leading to multiple sclerosis and other demyelinating diseases.2 Metachromatic leukodystrophy is an inherited disorder characterized by a deficiency of the lysosomal enzyme arylsulfatase A and the subsequent accumulation of sulfatide in neural and visceral tissues.3 Sulfatide also regulates the differentiation of oligodendroblasts. Central nervous system (CNS) myelin is strongly inhibitory to growing axons and sulfatides present in the myelin of the CNS have been identified as major myelin-associated axon growth inhibitors.4 A low level of serum sulfatides has been linked with an increased risk of cardiovascular disease in some situations. Sulfatides in the myelin, especially cis-tetracosenoyl-sulfatides, stimulate a distinct population of CD1d-restricted natural killer T cells giving these sulfatides important implications for the design of therapeutics that target T cells reactive for myelin glycolipids in autoimmune diseases of the central nervous system.5

保存建议：N-十二烷酰硫-N-Dodecanoyl-sulfatide对于本产品，我们推荐使用-20℃蓝冰低温进行运输。在您收到货物后，我们建议在-20℃温度下冷冻保存，溶解使用说明请参考本品说明。

产品描述：N-C12:0-sulfatide|N-Dodecanoyl-sphingosyl-beta-D-galactoside-3-sulfate

点击：N-十二烷酰硫-N-Dodecanoyl-sulfatide查看更详细产品说明，更多应用、储存、价格、货期等信息请致电垂询艾美捷科技有限公司。更多Matreya公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。

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