文献支持N-(R,S)-α-羟基十六烷酰基-D-赤型-二氢鞘氨醇|N-(R,S)-alpha-Hydroxyhexadecanoyl-D-erythro-dihydrosphingosine
价格: ¥11
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保存条件 :建议在-20℃温度下冷冻保存
保质期 :参考产品说明书
英文名 :N-(R,S)-alpha-Hydroxyhexadecanoyl-D-erythro-dihydrosphingosine
库存 :100
供应商 :艾美捷科技
CAS号 :无
规格 :5mg
N-(R,S)-α-羟基十六烷酰基-D-赤型-二氢鞘氨醇,N-(R,S)-alpha-Hydroxyhexadecanoyl-D-erythro-dihydrosphingosine,Hydroxydodecanoyl
产品名称:N-(R,S)-α-羟基十六烷酰基-D-赤型-二氢鞘氨醇-N-(R,S)-alpha-Hydroxyhexadecanoyl-D-erythro-dihydrosphingosine
产品货号:2047-5
产品规格:5mg
背景资料:This product is a high purity alpha-hydroxydihydroceramide and is ideal as a standard and for biological studies. Dihydroceramide is a critical intermediate in the synthesis of many complex sphingoid bases. Inhibition of dihydroceramide synthesis by some fungal toxins that have a similar structure causes an increase in sphinganine and sphinganine-1-phosphate and a decrease in other sphingolipids leading to a number of diseases including oesophageal cancer. Dihydroceramide, synthesized by the acylation of sphinganine, is subsequently converted into ceramide via a desaturase enzyme or into phytosphingosine via the C4-hydrozylase enzyme.1 The presence of a hydroxyl group on the fatty acyl chain of dihydroceramides significantly affects the function and properties of the molecule. While 2(S)-hydroxydihydroceramides can be converted to non-hydroxydihydroceramides in vivo 2(R)-hydroxydihydroceramides cannot. Data presented suggests that 2(R)-hydroxydihydroceramides may interact with some distinct cellular regulatory targets in a specific and more effective manner than their nonhydroxylated analogs.2 2-hydroxydihydroceramides have been shown to be incorporated into the galactosylceramides and sulfatides of the myelin where they are essential to neuronal functions.3
保存建议:N-(R,S)-α-羟基十六烷酰基-D-赤型-二氢鞘氨醇-N-(R,S)-alpha-Hydroxyhexadecanoyl-D-erythro-dihydrosphingosine对于本产品,我们推荐使用-20℃蓝冰低温进行运输。在您收到货物后,我们建议在-20℃温度下冷冻保存,溶解使用说明请参考本品说明。
产品描述:N-(R,S)-alpha-Hydroxy-C16:0-D-erythro-dihydroceramide|N-(R,S)-alpha-Hydroxypalmitoyl-D-erythro-dihydrosphingosine
点击:N-(R,S)-α-羟基十六烷酰基-D-赤型-二氢鞘氨醇-N-(R,S)-alpha-Hydroxyhexadecanoyl-D-erythro-dihydrosphingosine查看更详细产品说明,更多应用、储存、价格、货期等信息请致电垂询艾美捷科技有限公司。更多Matreya公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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