文献支持神经酰胺（羟基）|Ceramides (hydroxy)

保存条件 ：建议在-20℃温度下冷冻保存

保质期 ：参考产品说明书

英文名 ：Ceramides (hydroxy)

库存 ：100

供应商 ：艾美捷科技

CAS号 ：无

规格 ：10mg

神经酰胺（羟基），Ceramides (hydroxy)，Ceramides

产品名称：神经酰胺（羟基）-Ceramides (hydroxy)

产品货号：1323-10

产品规格：10mg

背景资料：Ceramide is a fatty acid amide of sphingosine. This product contains ceramides with mostly 2-hydroxy fatty acids (alphahydroxy fatty acids). 2-hydroxy fatty acid ceramides are especially abundant in nervous and epidermal cells. These ceramides are important for the permeability barrier function of epidermis and the lipid organization in membranes. The 2- hydroxylation is catalyzed by fatty acid 2-hydroxylase (FA2H or fatty acid alpha-hydroxylase). Ceramide functions as a precursor in the synthesis of sphingomyelin, glycosphingolipids, and of free sphingosine and fatty acids. The sphingosine can be phosphorylated to form sphingosine-1-phosphate. Two of ceramide’s metabolites, sphingosine-1-phosphate and glucosylceramide, produce cell proliferation and other cellular functions.1 Ceramide exerts numerous biological effects, including induction of cell maturation, cell cycle arrest, terminal cell differentiation, cell senescence, and cell death.2 Because of these effects ceramide has been investigated for its use in cancer treatment and many potential approaches to cancer therapy have been presented.3 Other effects include producing reactive oxygen in mitochondria (followed by apoptosis) and stimulating phosphorylation of certain proteins (especially mitogen activated protein). It also stimulates some protein phosphatases (especially protein phosphatase 2A) making it an important controller of protein activity. Ceramides with short side chains have been shown to enter easily into cells where they are biologically active. Ceramides with longer side chains also enter cells if dissolved in dodecane-isopropanol first.

保存建议：神经酰胺（羟基）-Ceramides (hydroxy)对于本产品，我们推荐使用-20℃蓝冰低温进行运输。在您收到货物后，我们建议在-20℃温度下冷冻保存，溶解使用说明请参考本品说明。

产品描述：Ceramides, mostly with hydroxy acyl groups

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