EMB/ Embigin Antibody (Internal)

保存条件 ：Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

库存 ：100

宿主 ：Rabbit

靶点 ：Human EMB. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

规格 ：50 μg

分子量：
37kDa
细胞定位：
Antigen Cellular Localization:Cell membrane; Single-pass type I membrane protein. Cell junction, synapse. Note=Localizes to the neuromuscular junctions
形式：
Liquid
参考文献：
Ota T.,et al.Nat. Genet. 36:40-45(2004).Schmutz J.,et al.Nature 431:268-274(2004).Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.Wollscheid B.,et al.Nat. Biotechnol. 27:378-386(2009).
产品概述：
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality EMB/ Embigin antibody (Internal).
功能：
Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane (By similarity).
总结：
Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane (By similarity).
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