CCKAR / CCK1R Antibody (N-Terminus)

保存条件 ：Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

库存 ：100

宿主 ：Rabbit

靶点 ：Human CCKAR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

抗体名 ：CCKRA

规格 ：50 μg

分子量：
48kDa
细胞定位：
Antigen Cellular Localization:Cell membrane; Multi-pass membrane protein.
形式：
Liquid
参考文献：
Ulrich C.D.,et al.Biochem. Biophys. Res. Commun. 193:204-211(1993).Wank S.A.,et al.Biochem. Biophys. Res. Commun. 194:811-818(1993).Miller L.J.,et al.Gastroenterology 109:1375-1380(1995).Funakoshi A.,et al.FEBS Lett. 466:264-266(2000).Kopatz S.A.,et al.Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
产品概述：
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality CCKAR / CCK1R antibody (N-Terminus).
功能：
Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
总结：
Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
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