DAAM1 Antibody (N-term) [AMM08613G]

靶点 ：Disheveled-associated activator of morphogenesis 1, DAAM1, KIAA0666

浓度 ：Affinity Purification

应用范围 ：WB, IHC-P

宿主 ：Rabbit

适应物种 ：H

保质期 ：1-2年

供应商 ：安诺伦（北京）生物科技有限公司

克隆性 ：Polyclonal

保存条件 ：Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形态 ：Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原 ：This DAAM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-74 amino acids from the N-terminal region of human DAAM1.

规格 ：400 µl/200 µl/100 µl/50 µl

分子量：123473

细胞定位：Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Note=Perinuclear

功能：Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments. Involved in building functional cilia (PubMed:16630611, PubMed:17482208). Involved in the organization of the subapical actin network in multiciliated epithelial cells (By similarity). Together with DAAM2, required for myocardial maturation and sarcomere assembly (By similarity).

总结：Tissue Location:Expressed in all tissues examined.

稀释方法：WB--1:1000IHC-P--1:100~500