凋亡加强结构域蛋白15样蛋白抗体

供应商 ：江西江蓝纯生物试剂有限公司

库存 ：11

克隆性 ：单克隆

保质期 ：1年

抗体英文名 ：NLRC3

抗体名 ：凋亡加强结构域蛋白15样蛋白抗体

适应物种 ：人/动物/植物

应用范围 ：WB,ELISA等

浓度 ：1mg/ml

保存条件 ：-20 °

规格 ：100ul/200ul

产品货号 :  jlcR19282
英文名称 :  NLRC3
中文名称 : 凋亡加强结构域蛋白15样蛋白抗体
别    名 :  CARD15-like; CARD15-like protein; Caterpiller 16.2; Caterpiller protein 16.2; CLR16.2; FLJ00348; NLR family, CARD domain containing 3; Nlrc3; NLRC3_HUMAN; NOD-like receptor C3; NOD3; NOD3 protein; Nucleotide-binding oligomerization domain protein 3; Nucleotide-binding oligomerization domain protein 3 caterpiller 16.2; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 3; Protein NLRC3.  
研究领域 :  细胞生物  结合蛋白  淋巴细胞  t-淋巴细胞  
抗体来源 :  Rabbit
克隆类型 :  Polyclonal
交叉反应 :  Human, Mouse, Pig, Cow, Sheep,
产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 :  115kDa
细胞定位 :  细胞浆
性    状 :  Lyophilized or Liquid
浓    度 :  1mg/ml
免 疫 原 :  KLH conjugated synthetic peptide derived from human NLRC3:721-820/1065
亚    型 :  IgG
纯化方法 :  affinity purified by Protein A
储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed :  PubMed
产品介绍 :  This gene encodes a NOD-like receptor family member. The encoded protein is a cytosolic regulator of innate immunity. This protein directly interacts with stimulator of interferon genes (STING), to prevent its proper trafficking, resulting in disruption of STING-dependent activation of the innate immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

Function:
May modulate T-cell activation. Decreases the transcription of genes that are normally up-regulated after T-cell stimulation. Delays degradation of NFKBIA/IKBA.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Detected in peripheral blood mononuclear cells.

Similarity:
Belongs to the NLRP family.
Contains 16 LRR (leucine-rich) repeats.
Contains 1 NACHT domain.

SWISS:
Q7RTR2

Gene ID:
197358

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.