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AG-13958

CAS No. : 319460-94-1

MCE 国际站：AG-13958

产品活性：AG-13958 (AG-013958) 是一种有效的 VEGFR 酪氨酸激酶抑制剂，可用于研究年龄相关性黄斑变性 (AMD) 的脉络膜新生血管形成。

研究领域：Protein Tyrosine Kinase/RTK

作用靶点：VEGFR

In Vitro: AG-13958 (AG-013958) is ATP-competitive by tight-binding kinetic analysis when minigastrin (0.5 mM) is used as a substrate.

In Vivo: ST administration (Steroid injection) of AG-13958 suspension produces a depot of drug on the posterior surface of the sclera that provided sustained exposure to the choroid with little impact on peripheral tissues and no measurable systemic exposure.

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