NOGO66受体相关蛋白2抗体

供应商 ：江西江蓝纯生物试剂有限公司

库存 ：52

克隆性 ：单克隆

保质期 ：1年

抗体英文名 ：NgR2/RTN4RL2

抗体名 ：NOGO66受体相关蛋白2抗体

适应物种 ：人/动物/植物

应用范围 ：WB,ELISA等

浓度 ：1mg/ml

保存条件 ：-20 °

规格 ：100ul/200ul

产品货号 :  jlcR18889
英文名称 :  NgR2/RTN4RL2
中文名称 : NOGO66受体相关蛋白2抗体
别    名 :  NgR2; NGRH1; NGRL3; Nogo 66 receptor related protein 2; Nogo receptor-like 3; Nogo-66 receptor homolog 1; Nogo-66 receptor-related protein 2; R4RL2_HUMAN; Reticulon-4 receptor-like 2; RTN4RL2.  
研究领域 :  细胞生物  发育生物学  神经生物学  
抗体来源 :  Rabbit
克隆类型 :  Polyclonal
交叉反应 :  Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 :  41kDa
细胞定位 :  细胞膜
性    状 :  Lyophilized or Liquid
浓    度 :  1mg/ml
免 疫 原 :  KLH conjugated synthetic peptide derived from human NgR2/RTN4RL2:81-180/420
亚    型 :  IgG
纯化方法 :  affinity purified by Protein A
储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed :  PubMed
产品介绍 :   NgR2 belongs to the Nogo receptor family and contains eight LRR (leucine-rich) repeats, one LRRNT domain and a single LRRCT domain. The gene encoding NgR2 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Function:
May play a role in regulating axonal regeneration and plasticity in the adult central nervous system.

Subcellular Location:
Cell membrane

Tissue Specificity:
Highly expressed in brain and liver. Expressed at lower levels in kidney, mammary gland, placenta, skeletal muscle, spleen and thyroid.

Post-translational modifications:
Undergoes zinc metalloproteinase-mediated ectodomain shedding in neuroblastoma cells; where BRE is released as a full-length ectodomain and an N-terminal fragment containing the leucine-rich repeat (LRR) region of the protein.

Similarity:
Belongs to the Nogo receptor family.
Contains 8 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.

SWISS:
Q86UN3

Gene ID:
349667

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.