研选Human IL-6 High Sensitivity ELISA Kit(人白介素6 高敏ELISA试剂盒)
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库存 :99
供应商 :联科生物
检测限 :0.31 pg/mL - 20 pg/mL
检测方法 :双抗夹心法
应用 :ELISA
适应物种 :Human
标记物 :HRP
样本 :血清,血浆,细胞培养上清及其他生物学样本
规格 :24T
背景介绍 | 白细胞介素6(IL-6)是一种同时具备促炎性和抗炎性的细胞因子。在人类中,它由IL-6基因编码。在感染期间和受到外伤后,尤其是烧伤或其它组织损伤导致的炎症,IL-6会由T细胞和巨噬细胞分泌,促进免疫应答。研究表明,小鼠抵抗肺炎链球菌感染时需要IL-6的参与,说明IL-6在抵抗感染中发挥作用。 IL-6在很多疾病如糖尿病、动脉粥样硬化、抑郁症、阿尔茨海默氏病、系统性红斑狼疮、多发性骨髓瘤、前列腺癌、白塞氏病和类风湿性关节炎等中可促进炎性和自身免疫疾病进程。晚期/转移性癌症患者的血液中具有较高水平的IL-6。 |
检测原理 | 本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人IL-6抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体,经过孵育,样本中存在的IL-6与固相抗体和检测抗体结合。洗涤去除未结合的物质后,加入辣根过氧化物酶标记的链霉亲和素 (Streptavidin-HRP)。洗涤后,加入信号增强剂孵育,洗涤去除未结合的物质后,再次加入Streptavidin-HRP。洗涤后,加入显色底物TMB,避光显色。颜色反应的深浅与样本中IL-6的浓度成正比。加入终止液终止反应,在450 nm波长(参考波长570-630 nm)测定吸光度值。 |
组分 | 包被抗IL-6单克隆抗体的96孔聚苯乙烯酶标板 人IL-6冻干标准品 IL-6检测抗体 标准品稀释液 辣根过氧化物酶标记的链霉亲和素 信号增强剂浓缩液 信号增强剂稀释液 检测缓冲液(10×) 底物(TMB) 终止液 洗液(20×) 封板膜 |
分析类型 | 夹心ELISA |
样本类型 | 血清、血浆,细胞培养上清及其他生物学样本 |
板式 | 96孔板,可拆 |
保存 | 试剂盒未拆开,4℃保存。已拆开,标准品-20℃保存,其它4℃保存。 |
运输条件 | 4℃蓝冰运输 |
样本体积 | 血清血浆:20 μl 细胞培养上清:100μl |
灵敏度 | 0.02 pg/ml |
标曲图 | |
标准曲线范围 | 0.31-20 pg/ml |
回收率范围 | 74 %-119 % |
平均回收率 | 0.94 |
板间变异系数 | 4.6 %-6.7 % |
板内变异系数 | 4.7 %-5.6 % |
IL6 分子靶点信息概述
- 分子名:IL6, interleukin 6
- 基因家族:Interferons; Interleukins; Interleukin 6 type cytokine family
- 别名:IL-6; BSF2; HGF; HSF
- 曾用名:IFNB2
- 全称:interferon, beta 2; interleukin 6 (interferon, beta 2)
IL6 分子靶点综述
白细胞介素6(IL-6)是一种同时具备促炎性和抗炎性的细胞因子。在人类中,它由IL-6基因编码。在感染期间和受到外伤后,尤其是烧伤或其它组织损伤导致的炎症,IL-6会由T细胞和巨噬细胞分泌,促进免疫应答。研究表明,小鼠抵抗肺炎链球菌感染时需要IL-6的参与,说明IL-6在抵抗感染中发挥作用。IL-6在很多疾病如糖尿病、动脉粥样硬化、抑郁症、阿尔茨海默氏病、系统性红斑狼疮、多发性骨髓瘤、前列腺癌、白塞氏病和类风湿性关节炎等中可促进炎性和自身免疫疾病进程。晚期/转移性癌症患者的血液中具有较高水平的IL-6。
人 Human IL6 分子靶点信息
- 分子名:IL6, interleukin 6
- 别称:
- B cell stimulatory factor-2
- B-cell differentiation factor
- B-cell stimulatory factor 2
- BSF-2
- BSF2
- CDF
- CTL differentiation factor
- HGF
- HSF
- hybridoma growth factor
- IFN-beta-2
- IFNB2
- IL-6
- interferon beta-2
- interferon, beta 2
- interleukin BSF-2
- interleukin-6
- 基因序列:NCBI_Gene: 3569
- 蛋白序列:UniProtKB: P05231
人 Human IL6靶点分子功能(预测)
Enables cytokine activity and growth factor activity. Contributes to interleukin-6 receptor binding activity. Involved in several processes, including positive regulation of cell population proliferation; positive regulation of macromolecule metabolic process; and regulation of peptide hormone secretion. Acts upstream of or within several processes, including cellular response to lipopolysaccharide; positive regulation of leukocyte adhesion to vascular endothelial cell; and positive regulation of macromolecule metabolic process. Located in extracellular space. Part of interleukin-6 receptor complex. Implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and periodontal disease (multiple). Biomarker of several diseases, including autoimmune disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and lung disease (multiple).
- IF = 30.964 Akkermansia muciniphila protects mice against an emerging tick-borne viral pathogen. Nature Microbiology (2023)
- "
- IF = 27.287 The Akkermansia muciniphila Metabolite Harmaline Protects the Host From Systemic Viral Infection Through the Bile Acid-TGR5-NF-κB Axis. Cell Metabolism (2022)
- "
- IF = 22.553 Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis. IMMUNITY (2020)
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- IF = 11.161 CPEB3 inhibits epithelial-mesenchymal transition by disrupting the crosstalk between colorectal cancer cells and tumor-associated macrophages via IL-6R/STAT3 signaling. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2020)
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- IF = 4.932 Berberine inhibits dendritic cells differentiation in DSS-induced colitis by promoting Bacteroides fragilis. INTERNATIONAL IMMUNOPHARMACOLOGY (2021)
- IF = 4.932 IL-33 receptor expression on myeloid and plasmacytoid dendritic cells after allergen challenge in patients with allergic rhinitis. INTERNATIONAL IMMUNOPHARMACOLOGY (2021)
- IF = 4.932 Morin hydrate inhibits atherosclerosis and LPS-induced endothelial cells inflammatory responses by modulating the NFκB signaling-mediated autophagy. INTERNATIONAL IMMUNOPHARMACOLOGY (2021)
- IF = 4.927 Confusoside from Anneslea fragrans Alleviates Acetaminophen-Induced Liver Injury in HepG2 via PI3K-CASP3 Signaling Pathway. MOLECULES (2023)
- IF = 4.927 Influence of Molecular Weight of Polysaccharides from Laminaria japonica to LJP-Based Hydrogels: Anti-Inflammatory Activity in the Wound Healing Process. MOLECULES (2022)
- IF = 4.925 The nanomaterial-induced bystander effects reprogrammed macrophage immune function and metabolic profile. Nanotoxicology (2020)
- IF = 4.803 The Natural Alkaloid (−)-N-Hydroxyapiosporamide Suppresses Colorectal Tumor Progression as an NF-κB Pathway Inhibitor by Targeting the TAK1–TRAF6 Complex. JOURNAL OF NATURAL PRODUCTS (2023)
- IF = 4.711 Overexpression of TOLLIP Protects against Acute Kidney Injury after Paraquat Intoxication through Inhibiting NLRP3 Inflammasome Activation Modulated by Toll-Like Receptor 2/4 Signaling. MEDIATORS OF INFLAMMATION (2021)
- IF = 4.631 Fibrinogen-Like Protein 1 as a Novel Biomarker of Psoriasis Severity. Journal of Inflammation Research (2022)
- IF = 4.565 miR-146a is directly regulated by STAT3 in human hepatocellular carcinoma cells and involved in anti-tumor immune suppression. CELL CYCLE (2015)
- IF = 4.546 Gegen Qinlian standard decoction alleviated irinotecan-induced diarrhea via PI3K/AKT/NF-κB axis by network pharmacology prediction and experimental validation combination. Chinese Medicine (2023)
- IF = 4.534 Visfatin promotes intervertebral disc degeneration by inducing IL-6 expression through the ERK/JNK/p38 signalling pathways. Adipocyte (2021)
- IF = 4.451 Chlorogenic acid improves intestinal barrier function by downregulating CD14 to inhibit the NF-κB signaling pathway. Journal of Functional Foods (2021)
- IF = 4.432 Icariin arrests cell cycle progression and induces cell apoptosis through the mitochondrial pathway in human fibroblast-like synoviocytes. EUROPEAN JOURNAL OF PHARMACOLOGY (2021)
- IF = 4.419 NCOA4‐mediated ferritinophagy promoted inflammatory responses in periodontitis. JOURNAL OF PERIODONTAL RESEARCH (2021)
- IF = 4.4 Isobaric Tags for Relative and Absolute Quantitation (iTRAQ)-Based Proteomic Analysis of Hugan Qingzhi and Its Protective Properties against Free Fatty Acid-Induced L02 Hepatocyte Injury. Frontiers in Pharmacology (2017)
- IF = 4.38 AEG-1 silencing attenuates M2-polarization of glioma-associated microglia/macrophages and sensitizes glioma cells to temozolomide. Scientific Reports (2021)
- IF = 4.369 A Cross-sectional Study Reveals a Chronic Low-grade Inflammation in Achalasia. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2022)
- IF = 4.319 Protective Effect of Hedyotis diffusa Willd. Ethanol Extract on Isoniazid-Induced Liver Injury in the Zebrafish Model. Drug Design Development and Therapy (2022)
- IF = 4.319 Study on the Mechanism of Improving HIV/AIDS Immune Function with Jian Aikang Concentrated Pill Based on Network Pharmacology Combined with Experimental Validation. Drug Design Development and Therapy (2022)
- IF = 4.253 Enhanced T‐cell proliferation and IL‐6 secretion mediated by overexpression of TRIM21 in oral lesions of patients with oral lichen planus. JOURNAL OF ORAL PATHOLOGY & MEDICINE (2019)
- IF = 4.24 Peptide WCPFSRSF ameliorates excitotoxicity and elevates synaptic plasticity in glutamate-damaged SH-SY5Y cells by modulating the PI3K/mTOR/EIF4E and BDNF/CREB/TrkB pathways. Food Bioscience (2022)
- IF = 4.207 Participation of Increased Circulating MAIT Cells in Lung Cancer: a Pilot Study. Journal of Cancer (2022)
- IF = 4.174 Long noncoding RNA MIR3142HG accelerates lipopolysaccharide-induced acute lung injury via miR-95-5p/JAK2 axis. Human Cell (2022)
- IF = 4.162 Prunella vulgaris L. Attenuates Experimental Autoimmune Thyroiditis by Inhibiting HMGB1/TLR9 Signaling. Drug Design Development and Therapy (2021)
- IF = 4.157 Inflammatory Cytokines Changed in Patients With Depression Before and After Repetitive Transcranial Magnetic Stimulation Treatment. Frontiers in Psychiatry (2022)
- IF = 4.132 Weak UVB Irradiation Promotes Macrophage M2 Polarization and Stabilizes Atherosclerosis. Journal of Cardiovascular Translational Research (2021)
- IF = 4.102 Elevated latent transforming growth factor beta binding protein 2 in endometriosis promotes endometrial stromal cell invasion and proliferation via the NF-kB signaling pathway. MOLECULAR AND CELLULAR ENDOCRINOLOGY (2022)
- IF = 4.096 MiR-128-3p inhibits vascular smooth muscle cell proliferation and migration by repressing FOXO4/MMP9 signaling pathway. MOLECULAR MEDICINE (2020)
- IF = 4.084 RORγt inhibitor SR1001 alleviates acute pancreatitis by suppressing pancreatic IL-17-producing Th17 and γδ-T cells in mice with ceruletide-induced pancreatitis. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2021)
- IF = 4.06 Rectal administration of Panax notoginseng and Colla Corii Asini suppositories in ulcerative colitis: clinical effect and influence on immune function. American Journal of Translational Research (2022)
- IF = 4.054 Impaired myeloid-derived suppressor cells are associated with recurrent implantation failure: A case-control study. JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2021)
- IF = 4.047 Clonorchis sinensis granulin promotes malignant transformation of human intrahepatic biliary epithelial cells through interaction with M2 macrophages via regulation of STAT3 phosphorylation and the MEK/ERK pathway. Parasites & Vectors (2023)
- IF = 4.011 Loss of periodontal ligament fibroblasts by RIPK3-MLKL-mediated necroptosis in the progress of chronic periodontitis. Scientific Reports (2019)
- IF = 3.989 Alteration in the Cytokine Secretion of Bone Marrow Stromal Cells from Patients with Chronic Myelomonocytic Leukemia Contribute to Impaired Hematopoietic Supportive Activity. Stem Cells International (2018)
- IF = 3.984 Expression profile of PU.1 in CD4+T cells from patients with systemic lupus erythematosus. CLINICAL AND EXPERIMENTAL MEDICINE (2021)
- IF = 3.978 CircUBE3B High Expression Participates in Sevoflurane-Induced Human Hippocampal Neuron Injury via Targeting miR-326 and Regulating MYD88 Expression. NEUROTOXICITY RESEARCH (2022)
- IF = 3.969 Progesterone-induced blocking factor-mediated Th1/Th2 balance correlates with fetal arrest in women who underwent in vitro fertilization and embryo transfer. CLINICAL IMMUNOLOGY (2021)
- IF = 3.932 Isorhamnetin inhibits amplification of influenza A H1N1 virus inflammation mediated by interferon via the RIG-I/JNK pathway. Annals of Translational Medicine (2021)
- IF = 3.926 Colorable role of interleukin (IL)-6 in obesity hypertension: A hint from a Chinese adult case-control study. CYTOKINE (2023)
- IF = 3.923 Galectin‐3 exacerbates ox‐LDL‐mediated endothelial injury by inducing inflammation via integrin β1‐RhoA‐JNK signaling activation. JOURNAL OF CELLULAR PHYSIOLOGY (2018)
- IF = 3.909 Nucleotide-binding oligomerization domain (NOD) plays an important role in neonatal infection. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)
- IF = 3.861 Aconiti Lateralis Radix Praeparata lipid-soluble alkaloids alleviates IL-1β-induced inflammation of human fibroblast-like synoviocytes in rheumatoid arthritis by inhibiting NF-κB and MAPKs signaling pathways and inducing apoptosis. CYTOKINE (2022)
- IF = 3.84 SNHG15 knockdown inhibits diabetic nephropathy progression in pediatric patients by regulating the miR-141/ICAM-1 axis in vitro. BIOSCIENCE REPORTS (2021)
- IF = 3.758 Monocytes Undergo Functional Reprogramming to Generate Immunosuppression through HIF-1α Signaling Pathway in the Late Phase of Sepsis. MEDIATORS OF INFLAMMATION (2020)
- IF = 3.758 CD137 Signaling Promotes Endothelial Apoptosis by Inhibiting Nrf2 Pathway, and Upregulating NF-κB Pathway. MEDIATORS OF INFLAMMATION (2020)
- IF = 3.758 hnRNPA2/B1 Ameliorates LPS-Induced Endothelial Injury through NF-κB Pathway and VE-Cadherin/β-Catenin Signaling Modulation In Vitro. MEDIATORS OF INFLAMMATION (2020)
- IF = 3.747 Hexokinase 2-mediated glycolysis supports inflammatory responses to Porphyromonas gingivalis in gingival fibroblasts. BMC Oral Health (2023)
- IF = 3.739 P38 MAPK, NF-κB, and JAK-STAT3 Signaling Pathways Involved in Capecitabine-Induced Hand-Foot Syndrome via Interleukin 6 or Interleukin 8 Abnormal Expression. CHEMICAL RESEARCH IN TOXICOLOGY (2022)
- IF = 3.69 Bu-Shen-Fang-Chuan formula attenuates cigarette smoke-induced inflammation by modulating the PI3K/Akt-Nrf2 and NF-κB signalling pathways. JOURNAL OF ETHNOPHARMACOLOGY (2020)
- IF = 3.685 Alantolactone induces G1 phase arrest and apoptosis of multiple myeloma cells and overcomes bortezomib resistance. APOPTOSIS (2015)
- IF = 3.659 Tumor associated neutrophils promote the metastasis of pancreatic ductal adenocarcinoma. CANCER BIOLOGY & THERAPY (2020)
- IF = 3.654 Promotion of angiogenesis in vitro by Astragalus polysaccharide via activation of TLR4 signaling pathway. JOURNAL OF FOOD BIOCHEMISTRY (2022)
- IF = 3.652 Hesperidin alleviates bupivacaine anesthesia-induced neurotoxicity in SH-SY5Y cells by regulating apoptosis and oxidative damage. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2021)
- IF = 3.651 Mesenchymal stem cells pretreated with proinflammatory cytokines accelerate skin wound healing by promoting macrophages migration and M2 polarization. Regenerative Therapy (2022)
- IF = 3.644 Acute Phase Serum Leptin, Adiponectin, Interleukin-6, and Visfatin Are Altered in Chinese Children With Febrile Seizures: A Cross-Sectional Study. Frontiers in Endocrinology (2020)
- IF = 3.633 Vitamin D deficiency is associated with thyroid autoimmunity: results from an epidemiological survey in Tianjin, China. ENDOCRINE (2021)
- IF = 3.606 Downregulating lncRNA PRNCR1 ameliorates LPS-induced pulmonary vascular endothelial cell injury by modulating miR-330-5p/TLR4 axis. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2020)
- IF = 3.6 Angiotensin II type 2 receptor agonist attenuates LPS-induced acute lung injury through modulating THP-1-derived macrophage reprogramming. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2023)
- IF = 3.575 Glycerophospholipid metabolism is involved in rheumatoid arthritis pathogenesis by regulating the IL-6/JAK signaling pathway. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2022)
- IF = 3.534 Elevated Peripheral Frequencies of Th22 Cells: A Novel Potent Participant in Obesity and Type 2 Diabetes. PLoS One (2014)
- IF = 3.525 Hydrofluoric acid and nitric acid cotreatment for biofunctionalization of polyetheretherketone in M2 macrophage polarization and osteogenesis. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2020)
- IF = 3.5 Potential salivary and serum biomarkers for burning mouth syndrome and their relationship with anxiety/depression. Journal of Dental Sciences (2023)
- IF = 3.47 Gypenosides Protect Orbital Fibroblasts in Graves Ophthalmopathy via Anti-Inflammation and Anti-Fibrosis Effects. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2020)
- IF = 3.452 Infant immune response to hepatitis B vaccine after fetal exposure to telbivudine. Human Vaccines & Immunotherapeutics (2022)
- IF = 3.448 Effects of β2/aβ2 on oxLDL-induced CD36 activation in THP-1 macrophages. LIFE SCIENCES (2019)
- IF = 3.414 Phillygenin inhibits LPS-induced activation and inflammation of LX2 cells by TLR4/MyD88/NF-κB signaling pathway. JOURNAL OF ETHNOPHARMACOLOGY (2019)
- IF = 3.411 Soluble B7-H5 Is a Novel Diagnostic, Severity, and Prognosis Marker in Acute Pancreatitis. Biomed Research International (2021)
- IF = 3.402 Matrine increases NKG2D ligand ULBP2 in K562 cells via inhibiting JAK/STAT3 pathway: a potential mechanism underlying the immunotherapy of matrine in leukemia. American Journal of Translational Research (2015)
- IF = 3.399 NANOG Promotes Cell Proliferation, Invasion, and Stemness via IL-6/STAT3 Signaling in Esophageal Squamous Carcinoma:. TECHNOLOGY IN CANCER RESEARCH & TREATMENT (2021)
- IF = 3.393 BRAFV600E mutant colorectal cancer cells mediate local immunosuppressive microenvironment through exosomal long noncoding RNAs. World Journal of Gastrointestinal Oncology (2021)
- IF = 3.375 TRIM21 causes abnormal expression of IL-6 in oral lichen planus via the TRIB2-MAPK signal axis. American Journal of Translational Research (2020)
- IF = 3.361 Platelet-derived growth factor B attenuates lethal sepsis through inhibition of inflammatory responses. INTERNATIONAL IMMUNOPHARMACOLOGY (2019)
- IF = 3.361 Estrogen facilitates gastric cancer cell proliferation and invasion through promoting the secretion of interleukin-6 by cancer-associated fibroblasts. INTERNATIONAL IMMUNOPHARMACOLOGY (2019)
- IF = 3.361 CXCL16/CXCR6 axis promotes bleomycin-induced fibrotic process in MRC-5 cells via the PI3K/AKT/FOXO3a pathway. INTERNATIONAL IMMUNOPHARMACOLOGY (2019)
- IF = 3.361 Interleukin-25 is upregulated in patients with systemic lupus erythematosus and ameliorates murine lupus by inhibiting inflammatory cytokine production. INTERNATIONAL IMMUNOPHARMACOLOGY (2019)
- IF = 3.357 The clinical study on treatment of CD19-directed chimeric antigen receptor-modified T cells in a case of refractory Richter syndrome. Cancer Medicine (2019)
- IF = 3.342 MicroRNA-122-5p regulates coagulation and inflammation through MASP1 and HO-1 genes. INFECTION GENETICS AND EVOLUTION (2022)
- IF = 3.297 Ex vivo lung perfusion with perfusate purification for human donor lungs following prolonged cold storage. Annals of Translational Medicine (2020)
- IF = 3.269 Timosaponin B-II alleviates osteoarthritis-related inflammation and extracellular matrix degradation through inhibition of mitogen-activated protein kinases and nuclear factor-κB pathways in vitro. Bioengineered (2022)
- IF = 3.269 Suppression of NOD-like receptor protein 3 inflammasome activation and macrophage M1 polarization by hederagenin contributes to attenuation of sepsis-induced acute lung injury in rats. Bioengineered (2022)
- IF = 3.263 Anthocyanin ameliorates hypoxia and ischemia induced inflammation and apoptosis by increasing autophagic flux in SH-SY5Y cells. EUROPEAN JOURNAL OF PHARMACOLOGY (2020)
- IF = 3.244 miR‐141‐3p inhibits vascular smooth muscle cell proliferation and migration via regulating Keap1/Nrf2/HO‐1 pathway. IUBMB LIFE (2020)
- IF = 3.244 Atorvastatin inhibits renal inflammatory response induced by calcium oxalate crystals via inhibiting the activation of TLR4/NF‐κB and NLRP3 inflammasome. IUBMB LIFE (2020)
- IF = 3.242 Liraglutide regulates bone destruction and exhibits anti-inflammatory effects in periodontitis in vitro and in vivo. JOURNAL OF DENTISTRY (2020)
- IF = 3.234 Overexpression of Forkhead box C1 attenuates oxidative stress, inflammation and apoptosis in chronic obstructive pulmonary disease. LIFE SCIENCES (2018)
- IF = 3.234 Single Administration of Ultra-Low-Dose Lipopolysaccharide in Rat Early Pregnancy Induces TLR4 Activation in the Placenta Contributing to Preeclampsia. PLoS One (2015)
- IF = 3.212 Insulin Exacerbates Inflammation in Fibroblast-Like Synoviocytes. INFLAMMATION (2020)
- IF = 3.212 Modulating macrophage polarization on titanium implant surface by poly(dopamine)-assisted immobilization of IL4. Clinical Implant Dentistry and Related Research (2019)
- IF = 3.208 Paclitaxel alleviated sepsis-induced acute lung injury by activating MUC1 and suppressing TLR-4/NF-κB pathway. Drug Design Development and Therapy (2019)
- IF = 3.153 Human Neural Stem Cell-Conditioned Medium Inhibits Inflammation in Macrophages Via Sirt-1 Signaling Pathway In Vitro and Promotes Sciatic Nerve Injury Recovery in Rats. STEM CELLS AND DEVELOPMENT (2020)
- IF = 3.149 Plasma biomarkers and delirium in critically ill patients after cardiac surgery: A prospective observational cohort study. HEART & LUNG (2023)
- IF = 3.146 Interleukin 1β and tumor necrosis factor α promote hFOB1.19 cell viability via activating AP1. American Journal of Translational Research (2016)
- IF = 3.144 Human bone marrow mesenchymal stem cells-derived exosomes protect against nerve injury via regulating immune microenvironment in neonatal hypoxic-ischemic brain damage model. IMMUNOBIOLOGY (2022)
- IF = 3.138 Different effects of lipoteichoic acid from C. butyricum and S. aureus on inflammatory responses of HT-29 cells. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2016)
- IF = 3.094 High Glucose-Induced Human Kidney Cell Apoptosis and Inflammatory Injury Are Alleviated by Circ_0008529 Knockdown via Circ_0008529-Mediated miR-485-5p/WNT2B Signaling. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2022)
- IF = 3.078 Expression of RANKL by peripheral neutrophils and its association with bone mineral density in COPD. RESPIROLOGY (2016)
- IF = 3.064 FGL2 regulates IKK/NF-κB signaling in intestinal epithelial cells and lamina propria dendritic cells to attenuate dextran sulfate sodium-induced colitis. MOLECULAR IMMUNOLOGY (2019)
- IF = 3.061 Serum NOX2 as a new biomarker candidate for HBV-related disorders. American Journal of Translational Research (2018)
- IF = 3.046 IFN-γ and TNF-α aggravate endothelial damage caused by CD123-targeted CAR T cell. OncoTargets and Therapy (2019)
- IF = 3.041 Introduction of exogenous wild‑type p53 mediates the regulation of oncoprotein 18/stathmin signaling via nuclear factor‑κB in non‑small cell lung cancer NCI‑H1299 cells. ONCOLOGY REPORTS (2019)
- IF = 3.024 MiR-340 suppresses CCl4-induced acute liver injury through exerting anti-inflammation targeting Sigirr.. European Review for Medical and Pharmacological Sciences (2020)
- IF = 3.018 The EGFR pathway is involved in the regulation of PD-L1 expression via the IL-6/JAK/STAT3 signaling pathway in EGFR-mutated non-small cell lung cancer. INTERNATIONAL JOURNAL OF ONCOLOGY (2016)
- IF = 3.018 Triptolide decreases expression of latency-associated nuclear antigen 1 and reduces viral titers in Kaposi's sarcoma-associated and herpesvirus-related primary effusion lymphoma cells. INTERNATIONAL JOURNAL OF ONCOLOGY (2016)
- IF = 2.967 Accumulation of T‑helper 22 cells, interleukin‑22 and myeloid‑derived suppressor cells promotes gastric cancer progression in elderly patients. Oncology Letters (2018)
- IF = 2.952 Serum‑derived exosomes from house dust mite‑sensitized guinea pigs contribute to inflammation in BEAS‑2B cells via the TLR4‑NF‑κB pathway. Molecular Medicine Reports (2021)
- IF = 2.942 Cimifugin ameliorates imiquimod-induced psoriasis by inhibiting oxidative stress and inflammation via NF-κB/MAPK pathway. BIOSCIENCE REPORTS (2020)
- IF = 2.94 Comparison and relationship of thyroid hormones, IL-6, IL-10 and albumin as mortality predictors in case-mix critically ill patients. CYTOKINE (2016)
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