UNC13D Polyclonal Antibody

供应商 ：Bio-Swamp

库存 ：800

靶点 ：UNC13D

克隆性 ：多克隆

抗体英文名 ：UNC13D Antibody

抗体名 ：UNC13D 抗体

宿主 ：Rabbit

适应物种 ：Human,Mouse

亚型 ：IgG

应用范围 ：WB,ELISA,IHC

规格 ：10μl/20μl/50μl/100μl

Product Information： 

 

Product name	UNC13D Polyclonal Antibody
Isotype	IgG
Form	Lyophilized or Liquid
Tested applications	WB,ELISA,IHC
Species reactivity	Human,Mouse
Host Species	Rabbit
Purity	Affinity purification

 

 

Immunogen Information：

 

 

Immunogen	Recombinant protein of human UNC13D
Calculated molecular weight	41kDa/123kDa/128kDa
Observed molecular weight	125kDa
Swiss Prot	Q70J99
Gene ID (NCBI)	201294
Alternative Names	FHL3;HLH3;HPLH3;Munc13-4

 

 

 

 

Application Notes：

 

 

 

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB	1:1000 - 1:2000
IHC	1:50 - 1:500

 

                           

Western blot analysis of extracts of various cell lines, using UNC13D antibody.

 

Background：

 

This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.  

 

Storage：

 

Storage instructions

Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.