ADD1 Polyclonal Antibody

靶点 ：ADD1

克隆性 ：多克隆

抗体英文名 ：ADD1 Polyclonal Antibody

抗体名 ：ADD1 Polyclonal Antibody

宿主 ：Rabbit

适应物种 ：Human,Mouse

亚型 ：IgG

形态 ：Lyophilized or Liquid

应用范围 ：WB,ELISA,IHC

保存条件 ：-20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

规格 ：10μl/20μl/50μl/100μl

Product Information： 

Product name	ADD1 Polyclonal Antibody
Isotype	IgG
Form	Lyophilized or Liquid
Tested applications	WB,ELISA,IHC
Species reactivity	Human,Mouse
Host Species	Rabbit
Purity	Affinity purification

 

Immunogen Information：

  

Immunogen	Recombinant protein of human ADD1
Calculated molecular weight	56kDa/69kDa/73kDa/80kDa/84kDa
Observed molecular weight	70kDa
Swiss Prot	P35611
Gene ID (NCBI)	118
Alternative Names	ADDA

 

Application Notes：

 

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB	1:500 - 1:2000
IHC	1:50 - 1:500

 

                           

Western blot analysis of extracts of various cell lines, using ADD1 antibody.

                                  

Background：

 

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.                         

  

Storage：

 

Storage instructions

Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.