ITGAM Polyclonal Antibody

靶点 ：ITGAM

克隆性 ：多克隆

抗体英文名 ：ITGAM Polyclonal Antibody

抗体名 ：ITGAM Polyclonal Antibody

宿主 ：Rabbit

适应物种 ：Human,Mouse,Rat

亚型 ：IgG

形态 ：Lyophilized or Liquid

应用范围 ：WB,IHC,IF,ELISA

保存条件 ：-20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

规格 ：10μl/20μl/50μl/100μl

Product Information： 

Product name	ITGAM Polyclonal Antibody
Isotype	IgG
Form	Lyophilized or Liquid
Tested applications	WB,IHC,IF,ELISA
Species reactivity	Human,Mouse,Rat
Host Species	Rabbit
Purity	Affinity purification

 

Immunogen Information：

  

Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 20-330 of human CD11B
Calculated molecular weight	127kDa
Observed molecular weight	180kDa
Swiss Prot	P11215
Gene ID (NCBI)	3684
Alternative Names	ITGAM; CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6; integrin alpha-M

 

Application Notes：

 

 

WB	1:500 - 1:2000
IHC	1:50 - 1:200
IF	1:50 - 1:200

                             

Western blot analysis of extracts of various cell lines, using ITGAM antibody.

Immunofluorescence analysis of rat bone marrow using CD11B antibody

                                    

Immunofluorescence analysis of RAW264.7 cells using CD11B antibody

Immunofluorescence analysis of THP-1 cells using CD11B antibody

 

Background：

 

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.  

 

Storage：

 

Storage instructions

Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.