8号染色体开放阅读框80抗体

供应商 ：江西江蓝纯生物试剂有限公司

库存 ：141

克隆性 ：单克隆

保质期 ：1年

抗体英文名 ：C8orf80

抗体名 ：8号染色体开放阅读框80抗体

适应物种 ：人/动物/植物

应用范围 ：WB,ELISA等

浓度 ：1mg/ml

保存条件 ：-20 °

规格 ：100ul/200ul

产品货号 :  jlcR20053
英文名称 :  C8orf80
中文名称 :  8号染色体开放阅读框80抗体
别    名 :  C8orf80; GTPase SLIP-GC; SLIP_HUMAN; Speckled-like pattern in the germinal center.   
研究领域 :  细胞生物  信号转导  
抗体来源 :  Rabbit
克隆类型 :  Polyclonal
交叉反应 :  Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
产品应用 :  ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 :  91kDa
细胞定位 :  细胞核
性    状 :  Lyophilized or Liquid
浓    度 :  1mg/ml
免 疫 原 :  KLH conjugated synthetic peptide derived from human C8orf80:601-700/796
亚    型 :  IgG
纯化方法 :  affinity purified by Protein A
储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed :  PubMed
产品介绍 :  Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. The C8orf80 gene product has been provisionally designated C8orf80 pending further characterization.

Function:
Plays a role as replication-related GTPase protein in germinal center B-cell.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in germinal center B-cell and in lymphomas derived from germinal center B-cell.

SWISS:
Q68CJ6

Gene ID:
389643

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.