精神障碍相关GAP蛋白抗体

供应商 ：江西江蓝纯生物试剂有限公司

库存 ：182

克隆性 ：单克隆

保质期 ：1年

抗体英文名 ：srGAP3

抗体名 ：精神障碍相关GAP蛋白抗体

适应物种 ：人/动物/植物

应用范围 ：WB,ELISA等

浓度 ：1mg/ml

保存条件 ：-20 °

规格 ：100ul/200ul

产品货号 :  jlcR3660
英文名称 :  srGAP3
中文名称 : 精神障碍相关GAP蛋白抗体
别    名 :  ARHGAP 14; ARHGAP14; Gbi; ME GAP; MEGAP; Mental disorder associated GAP; Rho GTPase activating protein 14; SLIT ROBO Rho GTPase activating protein 3; srGAP 2; srGAP 3; srGAP2; SRGP 2; SRGP2; WAVE associated Rac GTPase activating protein; WRP.  
研究领域 :  免疫学  神经生物学  激酶和磷酸酶  
抗体来源 :  Rabbit
克隆类型 :  Polyclonal
交叉反应  :  Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
产品应用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 :  121kDa
细胞定位 :  细胞浆
性    状 :  Lyophilized or Liquid
浓    度 :  1mg/ml
免 疫 原 :  KLH conjugated synthetic peptide derived from human srGAP3:201-300/1099
亚    型 :  IgG
纯化方法 :  affinity purified by Protein A
储 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed :  PubMed
产品介绍 :   srGAP3 (SLIT ROBO Rho GTPase-activating protein 3) is a GTPase activating protein (GAP) for the small G protein Rac. It has a putative role in attenuating Rac1 signalling in neurons. srGAP3 is thought to act downstream of the Slit-Robo pathway, which regulates neuronal migration and axonal branching, and play an important role in axonal regeneration after axotomy. It also plays a putative role in severe mental retardation.

Subunit:
Interacts with WASF1. Probably interacts with ROBO1. Interacts with FASLG.

Tissue Specificity:
Highly expressed in adult and fetal brain. Expressed at low levels in kidney. Isoform 3 is expressed in the kidney but is absent in the brain.

SWISS:
O43295

Gene ID:
9901

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.