AGT Polyclonal Antibody

靶点 ：AGT

克隆性 ：多克隆

抗体英文名 ：AGT Polyclonal Antibody

抗体名 ：AGT Polyclonal Antibody

宿主 ：Rabbit

适应物种 ：Human,Mouse

亚型 ：IgG

形态 ：Lyophilized or Liquid

应用范围 ：WB,ELISA,IHC

保存条件 ：-20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Product Information： 

Product name	AGT Polyclonal Antibody
Isotype	IgG
Form	Lyophilized or Liquid
Tested applications	WB,ELISA,IHC
Species reactivity	Human,Mouse
Host Species	Rabbit
Purity	Affinity purification

 

Immunogen Information：

 

Immunogen	Recombinant protein of human AGT
Calculated molecular weight	53kDa
Observed molecular weight	Refer to figures
Swiss Prot	P01019
Gene ID (NCBI)	183
Alternative Names	ANHU;hFLT1;SERPINA8

 

Application Notes：

   

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB	1:500 - 1:2000
IHC	1:50 - 1:500

     

Background：

 

The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.   

                                                                                

Storage：

 

Storage instructions

Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.