BAX Polyclonal Antibody

供应商 ：Bio-Swamp

库存 ：800

靶点 ：BAX

克隆性 ：多克隆

抗体英文名 ：BAX Antibody

抗体名 ：BAX 抗体

宿主 ：Rabbit

适应物种 ：Human,Mouse,Rat

亚型 ：IgG

应用范围 ：WB,IHC,IF,ELISA

规格 ：10 µl / 20 µl / 50 µl / 100 µl

Product Information： 

Product name	BAX Polyclonal Antibody
Isotype	IgG
Form	Lyophilized or Liquid
Tested applications	WB,IHC,IF,ELISA
Species reactivity	Human,Mouse,Rat
Host Species	Rabbit
Purity	Affinity purification

 

Immunogen Information：

  

Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human BAX
Calculated molecular weight	4kDa/12kDa/15kDa/18kDa/19kDa/21kDa/24kDa
Observed molecular weight	23kDa
Swiss Prot	Q07812
Gene ID (NCBI)	581
Alternative Names	BAX; BCL2L4; apoptosis regulator BAX

 

Application Notes：

 

WB	1:500 - 1:1000
IHC	1:50 - 1:100
IF	1:50 - 1:100

                                             

Western blot analysis of extracts of various cell lines, using BAX antibody.

Immunofluorescence analysis of C6 cells using BAX antibody.

                                              

Immunofluorescence analysis of NIH/3T3 cells using BAX antibody.		Immunofluorescence analysis of U2OS cells using BAX antibody.

 

Background：

 

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.   

 

Storage：

 

Storage instructions

Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.