CST3 Polyclonal Antibody

靶点 ：CST3

克隆性 ：多克隆

抗体英文名 ：CST3 Polyclonal Antibody

抗体名 ：CST3 Polyclonal Antibody

宿主 ：Rabbit

适应物种 ：Human,Mouse,Rat

亚型 ：IgG

形态 ：Lyophilized or Liquid

应用范围 ：WB,IF,ELISA,IHC

保存条件 ：-20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

规格 ：10μl/20μl/50μl/100μl

Product Information： 

Product name	CST3 Polyclonal Antibody
Isotype	IgG
Form	Lyophilized or Liquid
Tested applications	WB,IF,ELISA,IHC
Species reactivity	Human,Mouse,Rat
Host Species	Rabbit
Purity	Affinity purification

 

Immunogen Information：

 

Immunogen	Recombinant protein of human CST3
Calculated molecular weight	15kDa
Observed molecular weight	13kDa, 15kDa
Swiss Prot	P01034
Gene ID (NCBI)	1471
Alternative Names	ARMD11;HEL-S-2

 

Application Notes：

 

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB	1:500 - 1:2000
IF	1:10 - 1:100
IHC	1:50 - 1:500

 

                              

Western blot analysis of extracts of various cell lines, using CST3 antibody.

Western blot analysis of extracts of rat brain, using CST3 antibody.

Immunofluorescence analysis of HeLa cells using CST3 antibody.

     

Background：

 

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus. Alternative splicing results in multiple transcript variants encoding a single protein.                                                                                                                                         

 

Storage：

 

Storage instructions

Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.