NQO1 Polyclonal Antibody

靶点 ：NQO1

克隆性 ：多克隆

抗体英文名 ：NQO1 Polyclonal Antibody

抗体名 ：NQO1 Polyclonal Antibody

宿主 ：Rabbit

适应物种 ：Human,Mouse

亚型 ：IgG

形态 ：Lyophilized or Liquid

应用范围 ：WB,ELISA,IHC

保存条件 ：-20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

规格 ：10μl/20μl/50μl/100μl

Product Information： 

Product name	NQO1 Polyclonal Antibody
Isotype	IgG
Form	Lyophilized or Liquid
Tested applications	WB,ELISA,IHC
Species reactivity	Human,Mouse
Host Species	Rabbit
Purity	Affinity purification

 

Immunogen Information：

 

Immunogen	A synthetic peptide of human NQO1
Calculated molecular weight	26kDa/27kDa/30kDa
Observed molecular weight	32kDa
Swiss Prot	P15559
Gene ID (NCBI)	1728
Alternative Names	DHQU;DIA4;DTD;NMOR1;NMORI;QR1

 

Application Notes：

 

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB	1:500 - 1:2000
IHC	1:50 - 1:500

 

                          

Western blot analysis of extracts of various cell lines, using NQO1 antibody.

 

Background：

 

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.   

 

Storage：

 

Storage instructions

Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.