S100B Polyclonal Antibody

供应商 ：Bio-Swamp

库存 ：800

靶点 ：S100B

克隆性 ：多克隆

抗体英文名 ：S100B Antibody

抗体名 ：S100B 抗体

宿主 ：Rabbit

适应物种 ：Human,Mouse,Rat

亚型 ：IgG

应用范围 ：WB,IF,ELISA,IHC

规格 ：10 µl / 20 µl / 50 µl / 100 µl

Product Information： 

Product name	S100B Polyclonal Antibody
Isotype	IgG
Form	Lyophilized or Liquid
Tested applications	WB,IF,ELISA,IHC
Species reactivity	Human,Mouse,Rat
Host Species	Rabbit
Purity	Affinity purification

 

Immunogen Information：

 

Immunogen	Recombinant protein of human S100B
Calculated molecular weight	10kDa
Observed molecular weight	11kDa
Swiss Prot	P04271
Gene ID (NCBI)	6285
Alternative Names	NEF;S100;S100-B;S100beta

 

Application Notes：

 

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB	1:500 - 1:2000
IF	1:50 - 1:200
IHC	1:50 - 1:500

 

            

Western blot analysis of extracts of various cell lines, using S100B antibody.

 

Background：

 

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.   
 

Storage：

 

Storage instructions

Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.