免疫原 ：TEA domain family member 1 (SV40 transcriptional enhancer factor)

亚型 ：IgG

形态 ：liquid

保存条件 ：PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

克隆性 ：单克隆

适应物种 ：Human, Mouse ,Rat

保质期 ：12 month

库存 ：50

供应商 ：LSM bio

宿主 ： Rabbit

应用范围 ：ELISA,WB

浓度 ：≥95% as determined by SDS-PAGE

抗体英文名 ：anti-TEAD1 antibody,TEAD1 antibody

抗体名 ：anti-TEAD1 抗体,TEAD1 抗体

规格 ：100μg

TEAD1抗体| TEAD1 antibody

货号  PAab08581

蛋白别名  TCF13 antibody, TEF1

蛋白介绍

Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and cooperatively to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription in vivo in a cell-specific manner. The activation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF). Involved in cardiac development. Binds to the M-CAT motif.

产品描述

anti-TEAD1 antibody is a Rabbit Polyclonal antibody againstTEAD1..

建议稀释比例

IHC

Immunohistochemical of paraffin-embedded human trachea using 13518-1-AP(TEKT2 antibody) at dilution of 1:50

Western blot

mouse brain tissue were subjected to SDS PAGE followed by western blot with 13518-1-AP(TEKT2 antibody) at dilution of 1:300(本抗体仅供体外科研用途，不可用于临床诊断!)

 

武汉维克赛思科技有限公司

地址：武汉东湖新技术开发区东信路光谷创业街10栋

联系人：童经理

联系电话：13118103892
Email: info@vecscience.com

微信：13118103892

QQ: 3128136151