免疫原 ：recombination signal binding protein for immunoglobulin kappa J region

亚型 ：IgG

形态 ：liquid

保存条件 ：PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

克隆性 ：单克隆

适应物种 ：Human, Mouse

保质期 ：12 month

库存 ：50

供应商 ：LSM bio

宿主 ： Rabbit

应用范围 ：ELISA,WB,IHC,IP

浓度 ：≥95% as determined by SDS-PAGE

抗体英文名 ：anti-RBPJ antibody,RBPJ antibody

抗体名 ：anti-RBPJ 抗体,RBPJ 抗体

规格 ：100μg

RBPJ抗体| RBPJ antibody

货号  PAab07195

蛋白别名  IGKJRB antibody, IGKJRB1 antibody, RBPJK antibody, RBPSUH

蛋白介绍

Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Binds specifically to methylated DNA. Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4% oxygen) (PubMed:23303788).

产品描述

anti-RBPJ antibody is a Rabbit Polyclonal antibody againstRBPJ..

建议稀释比例

IHC

Immunohistochemistry of paraffin-embedded human pancreas cancer using PAab07195(RBPJ antibody) at dilution of 1:100

Western blot

mouse kidney tissue were subjected to SDS PAGE followed by western blot with PAab07195(RBPJ antibody) at dilution of 1:1000(本抗体仅供体外科研用途，不可用于临床诊断!)

 

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