免疫原 ：ataxia telangiectasia and Rad3 related

亚型 ：IgG

形态 ：liquid

保存条件 ：PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

克隆性 ：单克隆

适应物种 ：Human,Mouse ,Rat

保质期 ：12 month

库存 ：50

供应商 ：LSM bio

宿主 ： Rabbit

应用范围 ：ELISA,WB

浓度 ：≥95% as determined by SDS-PAGE

抗体英文名 ：anti-ATR antibody,ATR antibody

抗体名 ：anti-ATR 抗体,ATR 抗体

规格 ：100μg

ATR抗体| ATR antibody

货号  PAab00736

蛋白别名  FRP1

蛋白介绍

Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates BRCA1, CHEK1, MCM2, RAD17, RPA2, SMC1 and p53/TP53, which collectively inhibit DNA replication and mitosis and promote DNA repair, recombination and apoptosis. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at sites of DNA damage, thereby regulating DNA damage response mechanism. Required for FANCD2 ubiquitination. Critical for maintenance of fragile site stability and efficient regulation of centrosome duplication.

产品描述

anti-ATR antibody is a Rabbit Polyclonal antibody againstATR..

建议稀释比例

IHC

Western blot

(本抗体仅供体外科研用途，不可用于临床诊断!)

 

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