PARP1 Polyclonal Antibody

价格： ¥580 - 2980

品牌：Bio-Swamp

货号：PAB30003

产品详情

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供应商：Bio-Swamp

库存：100

靶点： PARP1

克隆性：多克隆

抗体英文名： PARP1 Antibody

抗体名： PARP1抗体

宿主：Rabbit

适应物种：Human,Mouse

亚型：IgG

应用范围：WB,IF,IHC,ELISA

保存条件：-20度冻存

规格： 10 µl / 20 µl / 50 µl / 100 µl

Product Information：

Product name	PARP1 Polyclonal Antibody
Isotype	IgG
Form	Lyophilized or Liquid
Tested applications	WB,IF,IHC,ELISA
Species reactivity	Human,Mouse
Host Species	Rabbit
Purity	Affinity purification

Immunogen Information：

Immunogen	A synthetic peptide of human PARP1
Calculated molecular weight	113kDa
Observed molecular weight	113kDa
Swiss Prot	P09874
Gene ID (NCBI)	142
Alternative Names	ADPRT;ADPRT1;ARTD1;pADPRT-1;PARP;PARP-1;PPOL

Application Notes：

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

WB	1:1000 - 1:2000
IF	1:50 - 1:200
IHC	1:50-1:500

Western blot analysis of extracts of Jurkat cells, using PARP1 antibody.

Western blot analysis of extracts of mouse testis, using PARP1 antibody.

Immunofluorescence analysis of NIH/3T3 cells using PARP1 antibody.

Immunofluorescence analysis of U2OS cells using PARP1 antibody.

Background：

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Storage：

Storage instructions

Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.