Recombinant Human BMP-13/CDMP-2 重组人BMP-13 / CDMP-2

价格：询价

品牌：Peprotech

货号：YJ120-04

产品详情

Recombinant Human BMP-13/CDMP-2

产品编号:

120-04

别名:

GDF-6,Cartilage-Derived Morphogenetic Protein-2 (CDMP-2)

描述:

BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains. This 27.5 kDa protein is obtained by proteolytic processing of a biologically inactive precursor protein of 97.7 kDa. Recombinant human BMP-13/CDMP-2 is a 27.0 kDa homodimeric disulfide-linked protein consisting of two 120 amino acid polypeptide chains.

氨基酸序列:

TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCR

来源:

E.coli

纯度:

Greater than 95% by SDS-PAGE gel and HPLC analyses.

生物活性:

The ED₅₀ was determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells in the range of 2.0-3.0 µg/ml.