Rap鸟嘌呤核苷酸交换因子3多克隆抗体/Rap鸟嘌呤核苷酸交换因子3多克隆抗体

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英文名 ：Epac Polyclonal Antibody

库存 ：现货

供应商 ：亚科因

CAS号 ：Null

规格 ：30μl///100μl///200μl

关键词：Epac抗体;Rap鸟嘌呤核苷酸交换因子3抗体;Rap鸟嘌呤核苷酸交换因子3;RAPGEF3; CGEF1; EPAC; EPAC1; Rap guanine nucleotide exchange factor 3; Exchange factor directly activated by cAMP 1; Exchange protein directly activated by cAMP 1; EPAC 1; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP;;ABP53470

中文名称：Rap鸟嘌呤核苷酸交换因子3多克隆抗体/Epac Polyclonal Antibody

英文名称：Epac Polyclonal Antibody

产品说明书：http://www.abbkine.cn/datasheet/ABP53470.pdf

产品描述：兔抗-Rap鸟嘌呤核苷酸交换因子3 多克隆抗体

RAPGEF3 (Rap Guanine Nucleotide Exchange Factor 3) is a Protein Coding gene. Among its related pathways are Platelet activation, signaling and aggregation and Signaling by GPCR. GO annotations related to this gene include guanyl-nucleotide exchange factor activity and cAMP-dependent protein kinase regulator activity. An important paralog of this gene is RASGEF1A. uanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin. TPases are a group of enzymes that catalyze hydrolysis of the gamma phosphate bond in guanine triphosphate (GTP) to form guanine diphosphate (GDP). Mg2+ ions are essential for catalytic activity. GTPases, often coupled to G proteins, are essential in signal transduction.

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