胶原蛋白I小鼠单克隆抗体 (1B2)/胶原蛋白I小鼠单克隆抗体 (1B2)

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英文名 ：Collagen I Mouse Monoclonal Antibody (1B2)

库存 ：现货

供应商 ：亚科因

CAS号 ：Null

规格 ：30μl///100μl///200μl

关键词：Collagen I抗体;胶原蛋白I小鼠抗体 ;胶原蛋白I小鼠 ;Collagen alpha-1(I) chain; Alpha-1 type I collagen;ABM40383

中文名称：胶原蛋白I小鼠单克隆抗体 (1B2)/Collagen I Mouse Monoclonal Antibody (1B2)

英文名称：Collagen I Mouse Monoclonal Antibody (1B2)

产品说明书：http://www.abbkine.cn/datasheet/ABM40383.pdf

产品描述：小鼠抗-胶原蛋白I 单克隆抗体 (1B2)

COL1A1 (collagen type I alpha 1 chain) encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in COL1A1 are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for COL1A1.

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